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CAS 62700-69-0

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1,2-Dioleoyl-sn-glycero-3-phosphoglycerol

Description:
1,2-Dioleoyl-sn-glycero-3-phosphoglycerol (DOPG) is a phospholipid that plays a significant role in cellular membranes, particularly in the formation of lipid bilayers. It is characterized by its two oleoyl fatty acid chains, which contribute to its fluidity and flexibility, making it an important component in membrane dynamics. DOPG has a glycerol backbone with a phosphate group, which imparts a polar head, allowing it to interact with aqueous environments. This amphiphilic nature enables DOPG to form vesicles and liposomes, which are utilized in drug delivery and nanotechnology. Additionally, DOPG is known to influence membrane properties such as curvature and permeability, and it can participate in various biological processes, including cell signaling and membrane fusion. Its CAS number, 62700-69-0, identifies it uniquely in chemical databases, facilitating research and application in biochemistry and pharmacology. Overall, DOPG is a vital component in both natural and synthetic lipid systems, contributing to the understanding of membrane biology and the development of lipid-based therapeutics.
Formula:C42H79O10P
InChI:InChI=1S/C42H79O10P/c1-3-5-7-9-11-13-15-17-19-21-23-25-27-29-31-33-41(45)49-37-40(38-51-53(47,48)50-36-39(44)35-43)52-42(46)34-32-30-28-26-24-22-20-18-16-14-12-10-8-6-4-2/h17-20,39-40,43-44H,3-16,21-38H2,1-2H3,(H,47,48)/b19-17-,20-18-/t39?,40-/m1/s1
InChI key:InChIKey=DSNRWDQKZIEDDB-GCMPNPAFSA-N
SMILES:[C@@H](COP(OCC(CO)O)(=O)O)(OC(CCCCCCC/C=C\CCCCCCCC)=O)COC(CCCCCCC/C=C\CCCCCCCC)=O
Synonyms:
  • Olein, 1,2-di-, 1-glycerophosphate
  • Dioleoylphosphatidylglycerol
  • 9-Octadecenoic acid (9Z)-, 1,1′-[(1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl] ester
  • 9-Octadecenoic acid (Z)-, 1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester, (1R)-
  • 9-Octadecenoic acid (9Z)-, (1R)-1-[[[(2,3-dihydroxypropoxy)hydroxyphosphinyl]oxy]methyl]-1,2-ethanediyl ester
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