CAS 6272-26-0

6-Hydroxy-2H-benzofuran-3-one

Description:

6-Hydroxy-2H-benzofuran-3-one, also known as coumarin-6, is a chemical compound characterized by its benzofuran structure, which features a fused benzene and furan ring system. This compound is notable for its hydroxyl group at the 6-position and a carbonyl group at the 3-position, contributing to its reactivity and potential biological activity. It typically appears as a white to pale yellow crystalline solid and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. 6-Hydroxy-2H-benzofuran-3-one is of interest in various fields, including medicinal chemistry and natural product synthesis, due to its potential pharmacological properties, including anti-inflammatory and antioxidant activities. Additionally, it serves as a precursor in the synthesis of other coumarin derivatives, which are widely studied for their diverse biological activities. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose health risks upon exposure.

Formula: C₈H₆O₃

InChI: InChI=1/C8H6O3/c9-5-1-2-6-7(10)4-11-8(6)3-5/h1-3,9H,4H2

InChI key: InChIKey=GBDMODVZBPFQKI-UHFFFAOYSA-N

SMILES: O=C1C=2C(OC1)=CC(O)=CC2

Synonyms:

• 3(2H)-Benzofuranone, 6-hydroxy-
• 6-Hydroxy-2,3-dihydro-1-benzofuran-3-one
• 6-Hydroxy-2,3-dihydrobenzo[b]furan-3-one
• 6-Hydroxy-2,3-dihydrobenzofuran-3-one
• 6-Hydroxy-3(2H)-benzofuranone
• 6-Hydroxy-3-coumaranone
• 6-Hydroxy-3-coumaranone~6-Hydroxy-2,3-dihydro-1-benzofuran-3-one
• 6-Hydroxybenzofuran-3(2H)-one
• 6-Hydroxybenzofuran-3-one
• 6-hydroxy-1-benzofuran-3(2H)-one
• NSC 37407
• 6-Hydroxy-2H-benzofuran-3-one

6-Hydroxy-3-coumaranone

CAS: 6272-26-0

Formula: C₈H₆O₃

Purity: >97.0%(GC)(T)

Color and Shape: Light yellow to Yellow to Orange powder to crystal

Molecular weight: 150.13

Ref: 3B-H1511

6-Hydroxy-2,3-dihydrobenzo[b]furan-3-one, 97%

CAS: 6272-26-0

6-Hydroxy-2,3-dihydrobenzo[b]furan-3-one, is used as a pharmaceutical intermediate. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item c

Formula: C₈H₆O₃

Purity: 97%

Color and Shape: Yellow to orange to brown, Crystals or powder or crystalline powder or fused solid

Molecular weight: 150.13

Ref: 02-L10951

6-Hydroxybenzofuran-3(2H)-one

CAS: 6272-26-0

Formula: C₈H₆O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 150.1314

Ref: IN-DA003N8D

6-Hydroxybenzo[b]furan-3(2H)-one

CAS: 6272-26-0

6-Hydroxybenzo[b]furan-3(2H)-one

Formula: C₈H₆O₃

Purity: 97%

Color and Shape: pale yellow solid

Molecular weight: 150.13g/mol

Ref: 54-OR7143

6-Hydroxy-2H-benzofuran-3-one

CAS: 6272-26-0

6-Hydroxy-2H-benzofuran-3-one is a potent inhibitor that blocks the formation of aurones and aldehydes, which are markers for insulin sensitivity. This compound has also been shown to inhibit dna replication in vitro by binding to the enzyme beta-diketone reductase (BDKR) and inhibiting its activity. 6-Hydroxy-2H-benzofuran-3-one is a fluorinated benzofuran derivative with an erythrocentaurin core structure. It has been shown to be effective against Gram positive bacteria, including methicillin resistant Staphylococcus aureus (MRSA). 6HBF3 also inhibits the growth of Gram negative bacteria, including Mycobacterium tuberculosis and Mycobacterium avium complex. The mechanism of action is not fully understood but may involve blocking lipid synthesis or preventing the synthesis of precursors for bacterial cell wall biosynthesis.

Formula: C₈H₆O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 150.13 g/mol

Ref: 3D-FH139688

6-Hydroxy-1-benzofuran-3(2H)-one

CAS: 6272-26-0

Formula: C₈H₆O₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 150.133

Ref: 10-F069222