CAS 627525-33-1

5-[3-(Difluoromethyl)-4-fluorophenyl]-3-[(2-methyl-1H-imidazol-1-yl)methyl]pyridazine

Description:

5-[3-(Difluoromethyl)-4-fluorophenyl]-3-[(2-methyl-1H-imidazol-1-yl)methyl]pyridazine, identified by its CAS number 627525-33-1, is a synthetic organic compound characterized by its complex molecular structure, which includes a pyridazine core substituted with various functional groups. The presence of a difluoromethyl group and a fluorophenyl moiety suggests potential applications in medicinal chemistry, particularly in the development of pharmaceuticals, due to the influence of fluorine on biological activity and lipophilicity. The imidazole ring contributes to the compound's potential for interacting with biological targets, possibly enhancing its pharmacological properties. This compound may exhibit specific solubility and stability characteristics influenced by its functional groups, making it suitable for various chemical reactions or formulations. Additionally, its unique structure may allow for selective interactions with enzymes or receptors, which is a critical aspect in drug design. Overall, the compound's characteristics suggest a promising avenue for research in drug discovery and development.

Formula: C₁₆H₁₃F₃N₄

InChI: InChI=1S/C16H13F3N4/c1-10-20-4-5-23(10)9-13-6-12(8-21-22-13)11-2-3-15(17)14(7-11)16(18)19/h2-8,16H,9H2,1H3

InChI key: InChIKey=BOVUHBFXPNLTKF-UHFFFAOYSA-N

SMILES: C(C1=CC(=CN=N1)C2=CC(C(F)F)=C(F)C=C2)N3C(C)=NC=C3

Synonyms:

• 5-[3-(Difluoromethyl)-4-fluorophenyl]-3-[(2-methyl-1H-imidazol-1-yl)methyl]pyridazine
• EVT 101
• 5-(3-Difluoromethyl-4-fluorophenyl)-3-(2-methylimidazol-1-ylmethyl)pyridazine
• ENS 101
• Pyridazine, 5-[3-(difluoromethyl)-4-fluorophenyl]-3-[(2-methyl-1H-imidazol-1-yl)methyl]-

EVT-101 free base

CAS: 627525-33-1

EVT-101 (ENS-101), a Roche-origin drug developed by Evotec, aims to treat depression by targeting NR2B.

Formula: C₁₆H₁₃F₃N₄

Color and Shape: Solid

Molecular weight: 318.3

Ref: TM-T68973