The chemical substance known as "(6S,8xi,9beta,11alpha,13E,15S)-11,15-dihydroxy-6,9-epoxyprost-13-en-1-oic acid," with the CAS number 62770-50-7, is a member of the prostaglandin family, which are bioactive lipids involved in various physiological processes. This compound features multiple hydroxyl groups, contributing to its polar nature and solubility in water and organic solvents. The presence of an epoxy group indicates a cyclic ether structure, which can influence its reactivity and biological activity. The stereochemistry, denoted by the specific configuration at various carbon centers, is crucial for its interaction with biological receptors, affecting its potency and efficacy. Prostaglandins are known for their roles in inflammation, pain modulation, and regulation of various bodily functions, including vascular tone and gastrointestinal activity. The specific structural features of this compound suggest potential therapeutic applications, although its exact biological role and mechanisms would require further investigation in pharmacological studies.

6β-
PGI
1
is a stable PGI
2
analog resistant to hydrolysis in aqueous solutions. 6β-
PGI
1
has a much longer half-
life than PGI
2
, but a greatly reduced molar potency for receptor mediated function. 6β-
PGI
1
has a K
act
for adenylate cyclase in NCB-
20 cells of 4.2 μM compared with 18 nM for PGI
2
. The potency for vasodilation and inhibition of platelet aggregation is about 1% of PGI
2
.
1
,
2

(6S,8xi,9beta,11alpha,13E,15S)-11,15-dihydroxy-6,9-epoxyprost-13-en-1-oic acid

62770-50-7: The chemical substance known as "(6S,8xi,9beta,11alpha,13E,15S)-11,15-dihydroxy-6,9-epoxyprost-13-en-1-oic acid," with the CAS number 62770-50-7, is a member of the prostaglandin family, which are bioactive lipids involved in various physiological processes. This compound features multiple hydroxyl groups, contributing to its polar nature and solubility in water and organic solvents. The presence of an epoxy group indicates a cyclic ether structure, which can influence its reactivity and biological activity. The stereochemistry, denoted by the specific configuration at various carbon centers, is crucial for its interaction with biological receptors, affecting its potency and efficacy. Prostaglandins are known for their roles in inflammation, pain modulation, and regulation of various bodily functions, including vascular tone and gastrointestinal activity. The specific structural features of this compound suggest potential therapeutic applications, although its exact biological role and mechanisms would require further investigation in pharmacological studies.

<p>6β-PGI1 is a stable PGI2 analog resistant to hydrolysis in aqueous solutions.</p>

CAS 62770-50-7

(6S,8xi,9beta,11alpha,13E,15S)-11,15-dihydroxy-6,9-epoxyprost-13-en-1-oic acid

6β-Prostaglandin I1

Ref: TM-T36239