CAS 6279-86-3

1,1,1-Triethyl methanetricarboxylate

Description:

1,1,1-Triethyl methanetricarboxylate, with the CAS number 6279-86-3, is an organic compound characterized by its structure, which includes three carboxylate groups attached to a central carbon atom that is also bonded to three ethyl groups. This compound is typically a colorless to pale yellow liquid with a fruity odor. It is soluble in organic solvents but has limited solubility in water due to its hydrophobic ethyl groups. The presence of multiple carboxylate functional groups imparts acidic properties, making it a potential candidate for various chemical reactions, including esterification and condensation. It is often used in organic synthesis and may serve as an intermediate in the production of pharmaceuticals, agrochemicals, or other fine chemicals. Safety data indicates that, like many organic compounds, it should be handled with care, as it may pose health risks if inhaled or ingested. Proper storage and handling procedures are essential to ensure safety in laboratory or industrial settings.

Formula: C₁₀H₁₆O₆

InChI: InChI=1S/C10H16O6/c1-4-14-8(11)7(9(12)15-5-2)10(13)16-6-3/h7H,4-6H2,1-3H3

InChI key: InChIKey=AGZPNUZBDCYTBB-UHFFFAOYSA-N

SMILES: C(C(OCC)=O)(C(OCC)=O)C(OCC)=O

Synonyms:

• 1,1,1-Triethyl methanetricarboxylate
• 2-Ethoxycarbonyl-malonic acid diethyl ester
• Diethyl (carboethoxy)malonate
• Diethyl (ethoxycarbonyl)malonate
• Diethyl 2-ethoxycarbonylmalonate
• Methanetricarboxylic acid triethyl ester~Tris(carboethoxy)methane
• Methanetricarboxylic acid, 1,1,1-triethyl ester
• Methanetricarboxylic acid, triethyl ester
• NSC 11006
• Tri(ethoxycarbonyl)methane
• Tricarbethoxymethane
• Tricarboethoxymethane
• Tris(ethoxycarbonyl)methane

Triethyl methanetricarboxylate, 98%

CAS: 6279-86-3

Methanetricarboxylates have been used as blocked malonic esters, restricting reaction with alkyl halides to monoalkylation. The unwanted carboxyl group can be removed by treatment with Na alkoxide, LDA or BCl3. Provides a useful 2-carbon chain extension method that adds to Michael acceptors under ph

Formula: C₁₀H₁₆O₆

Purity: 98%

Color and Shape: Colorless to white to pale yellow, Crystals or powder or crystalline powder or fused solid or clear liquid or viscous liquid as melt

Molecular weight: 232.23

Ref: 02-L08356

Triethyl methanetricarboxylate

CAS: 6279-86-3

Formula: C₁₀H₁₆O₆

Purity: 97%

Color and Shape: Liquid

Molecular weight: 232.2304

Ref: IN-DA003V1P

Triethyl methanetricarboxylate

CAS: 6279-86-3

Triethyl methanetricarboxylate

Purity: 98%

Molecular weight: 232.23044g/mol

Ref: 54-OR903316

Triethyl Methanetricarboxylate

CAS: 6279-86-3

Formula: C₁₀H₁₆O₆

Purity: >97.0%(GC)

Color and Shape: White or Colorless to Almost white or Almost colorless powder to lump to clear liquid

Molecular weight: 232.23

Ref: 3B-T1481

Triethyl Methanetricarboxylate

CAS: 6279-86-3

Formula: C₁₀H₁₆O₆

Molecular weight: 232.23

Ref: 4Z-C-347006

Triethyl Methanetricarboxylate

Controlled Product

CAS: 6279-86-3

Applications Triethyl Methanetricarboxylate is used in the synthesis of novel inhibitors of Hsp90. It is also used in the preparation of novel dihydroquinoline-3-carboxylic acids that function as HIV-1 integrase inhibitors.
References Day, J. et al.: Chem. A Eur. J., 16, 2758 (2010); Sechi, M. et al.: Bioorg. Med. Chem., 17, 2925 (2009);

Formula: C₁₀H₁₆O₆

Color and Shape: Neat

Molecular weight: 232.23

Ref: TR-T776680

2-Ethoxycarbonyl-malonic acid diethyl ester

CAS: 6279-86-3

Formula: C₁₀H₁₆O₆

Purity: 97%

Color and Shape: Liquid

Molecular weight: 232.232

Ref: 10-F049778