CAS 6285-05-8

1-(4-Chlorophenyl)-1-propanone

Description:

1-(4-Chlorophenyl)-1-propanone, also known as 4-Chlorobenzyl methyl ketone, is an organic compound characterized by its ketone functional group and a chlorinated aromatic ring. It has a molecular formula that reflects its structure, consisting of a propanone backbone with a para-chlorophenyl substituent. This compound typically appears as a colorless to pale yellow liquid with a distinctive odor. It is moderately soluble in organic solvents and has limited solubility in water due to its hydrophobic aromatic component. The presence of the chlorine atom enhances its reactivity, making it useful in various chemical syntheses, including the production of pharmaceuticals and agrochemicals. Additionally, it may exhibit biological activity, which can be of interest in medicinal chemistry. Safety precautions are necessary when handling this compound, as it may pose health risks, including irritation to the skin and respiratory system. Proper storage and disposal methods should be followed to mitigate environmental impact.

Formula: C₉H₉ClO

InChI: InChI=1/C9H9ClO/c1-2-9(11)7-3-5-8(10)6-4-7/h3-6H,2H2,1H3

InChI key: InChIKey=ADCYRBXQAJXJTD-UHFFFAOYSA-N

SMILES: C(CC)(=O)C1=CC=C(Cl)C=C1

Synonyms:

• 1-(4-Chlorophenyl)-1-propanone
• 1-Propanone, 1-(4-chlorophenyl)-
• Ethyl p-chlorophenyl ketone
• NSC 5600
• Propiophenone, 4′-chloro-
• p-Chloropropiophenone
• 4-Chloropropiophenone
• chloropropiophenone
• (P-CHLOROPHENYL)ACETONE
• 1-(4-CHLOROPHENYL)ACETONE
• 1-(4-chlorophenyl)-1-propanon
• 4-CHLOROPHENYLACETONE
• p-chloro-propiophenon
• 4-CHLOROPHENYL ETHYL KETONE
• 4’-chloro-propiophenon
• 1-(4-CHLOROPHENYL)PROPAN-2-ONE
• ART-CHEM-BB B028567
• AKOS B028567
• 4'-CHLOROPHENYLACETONE
• P-CHLORO BENZYL METHYL KETONE

4'-Chloropropiophenone

CAS: 6285-05-8

Formula: C₉H₉ClO

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 168.62

Ref: 3B-C1616

4'-Chloropropiophenone, 98%

CAS: 6285-05-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₉H₉ClO

Purity: 98%

Color and Shape: White to pale yellow, Crystals or crystalline powder or fused solid

Molecular weight: 168.62

Ref: 02-A11633

4'-Chloropropiophenone

CAS: 6285-05-8

Formula: C₉H₉ClO

Purity: 98%

Color and Shape: Solid

Molecular weight: 168.6202

Ref: IN-DA003L8B

4'-Chloropropiophenone

CAS: 6285-05-8

Formula: C₉H₉ClO

Purity: ≥ 98.0%

Color and Shape: White to off-white crystals or solid

Molecular weight: 168.62

Ref: 7W-GX1521

4'-Chloropropiophenone

CAS: 6285-05-8

4'-Chloropropiophenone

Formula: C₉H₉ClO

Purity: 98%

Color and Shape: white solid

Molecular weight: 168.62016g/mol

Ref: 54-OR11048

4'-Chloropropiophenone

Controlled Product

CAS: 6285-05-8

Applications 4-Chloropropiophenone is a useful synthetic intermediate. It can be used to prepare 4-Chloro Cathinone. It can also be used to synthesize bupropion (B689625) analogs.
References Carroll, F., et al.: J. Med. Chem., 52, 6768 (2009)

Formula: C₉H₉ClO

Color and Shape: Neat

Molecular weight: 168.62

Ref: TR-C379345

4'-Chloropropiophenone

CAS: 6285-05-8

4'-Chloropropiophenone is a synthetic, non-proteinaceous binding agent that is used in the reduction of benzene and carbonyl compounds. It can be prepared by reacting cyanoborohydride with amines in an acid-binding process. The reaction can be catalyzed by chloride or oxime. 4'-Chloropropiophenone binds to the carbonyl group of carbonyl compounds and forms a tetrahedral intermediate with the chloride ion. This intermediate is then reduced by an oxidant such as chromium trioxide, resulting in the formation of a new compound with a chloride substituent.

Formula: C₉H₉ClO

Purity: Min. 98%

Color and Shape: White Powder

Molecular weight: 168.62 g/mol

Ref: 3D-FC37749

4′-Chloropropiophenone

CAS: 6285-05-8

Formula: C₉H₉ClO

Purity: 96%

Color and Shape: Solid, White to very pale yellow powder

Molecular weight: 168.62

Ref: 10-F317876

4-Chloropropiophenone pure, 98%

CAS: 6285-05-8

Formula: C₉H₉CIO

Purity: min. 98%

Color and Shape: White, Crystalline powder

Molecular weight: 168.62

Ref: SR-53313