CAS 62865-36-5

Diclomezine

Description:

Diclomezine is a chemical compound classified as an antihistamine, primarily used for its antiemetic properties to alleviate symptoms of motion sickness and nausea. It functions by blocking histamine receptors in the body, which helps to reduce the sensation of nausea and vomiting. Diclomezine is typically administered in oral form and is known for its relatively low sedative effects compared to other antihistamines, making it a preferred choice for some patients. The compound has a moderate solubility in water and is more soluble in organic solvents, which influences its formulation in pharmaceutical preparations. Its chemical structure includes a phenothiazine moiety, contributing to its pharmacological activity. As with many medications, potential side effects may include drowsiness, dry mouth, and dizziness, and it is important for users to consult healthcare professionals regarding its use, especially in conjunction with other medications. Overall, Diclomezine serves as an effective option for managing nausea and motion sickness in various clinical settings.

Formula: C₁₁H₈Cl₂N₂O

InChI: InChI=1/C11H8Cl2N2O/c1-6-8(12)4-7(5-9(6)13)10-2-3-11(16)15-14-10/h2-5H,1H3,(H,15,16)

InChI key: InChIKey=UWQMKVBQKFHLCE-UHFFFAOYSA-N

SMILES: ClC=1C=C(C=C(Cl)C1C)C=2C=CC(=O)NN2

Synonyms:

• 3(2H)-Pyridazinone, 6-(3,5-dichloro-4-methylphenyl)-
• 6-(3,5-dichloro-4-methylphenyl)-3(2H)-pyridazinone
• 6-(3,5-dichloro-4-methylphenyl)pyridazin-3(2H)-one
• Monguard
• Diclomezine
• DICLOMEZINE STANDARD
• iclomezine
• sf-7531
• Brn 0884391
• Diclomezine [iso]
• diclomezine (bsi, draft e-iso, draft f-iso)
• Lindane Impurity 4-13C6 (Hexachlorobenzene-13C6 )
• 6-(3,5-DICHLORO-P-TOLYL)-PYRIDAZINE-3(2H)-ONE
• Dichlomezine
• 6-(3,5-dichloro-4-methylphenyl)-3(2h)-pyridazinon
• Diclomezine 100 μg/ml Methanol
• diclomezin
• Diclomezine 100 μg/mL in Acetone
• C12545000 Diclomezine

Diclomezine 100 µg/mL in Acetone

Controlled Product

CAS: 62865-36-5

Formula: C₁₁H₈Cl₂N₂O

Color and Shape: Single Solution

Molecular weight: 255.10

Ref: 04-XA12545000AC

Diclomezine

Controlled Product

CAS: 62865-36-5

Formula: C₁₁H₈Cl₂N₂O

Color and Shape: Neat

Molecular weight: 255.10

Ref: 04-C12545000

Diclomezin

Controlled Product

CAS: 62865-36-5

Formula: C₁₁H₈Cl₂N₂O

Color and Shape: Neat

Molecular weight: 255.10

Ref: TR-D437013

Diclomezin

CAS: 62865-36-5

Diclomezin is a medicinal analog that has been shown to inhibit the activity of tumor kinases in human cancer cells. It acts as an inhibitor of protein kinases, leading to apoptosis or programmed cell death in cancer cells. Diclomezin has been found to be effective against various types of cancers, including lung and breast cancers. This anticancer drug has also been shown to have a favorable safety profile, with no significant side effects reported in clinical trials. Diclomezin is excreted through urine and has been extensively studied as a potential therapeutic agent for cancer treatment. This inhibitor may have promising applications in the development of novel therapies for Chinese patients suffering from cancer.

Formula: C₁₁H₈Cl₂N₂O

Purity: Min. 95%

Molecular weight: 255.1 g/mol

Ref: 3D-MCA86536