CAS 628690-75-5

2′,4-Difluoro-5′-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl][1,1′-biphenyl]-2-carbonitrile

Description:

2′,4-Difluoro-5′-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl][1,1′-biphenyl]-2-carbonitrile, with CAS number 628690-75-5, is a synthetic organic compound characterized by its complex molecular structure, which includes multiple functional groups and fluorine atoms. The presence of difluoro and fluoro substituents suggests enhanced lipophilicity and potential biological activity, making it of interest in pharmaceutical research. The imidazopyridine moiety indicates potential interactions with biological targets, particularly in the context of kinase inhibition or other enzyme modulation. The carbonitrile group may contribute to the compound's reactivity and stability. This compound's unique structure may lead to specific pharmacokinetic properties, influencing its absorption, distribution, metabolism, and excretion (ADME) characteristics. Overall, the combination of fluorinated groups and heterocyclic structures positions this compound as a candidate for further investigation in medicinal chemistry, particularly in the development of targeted therapies.

Formula: C₂₃H₁₆F₃N₃O

InChI: InChI=1S/C23H16F3N3O/c1-23(2,30)18-7-8-29-20(12-28-22(29)21(18)26)13-3-6-19(25)17(10-13)16-5-4-15(24)9-14(16)11-27/h3-10,12,30H,1-2H3

InChI key: InChIKey=SJMMDWXJSSJHOQ-UHFFFAOYSA-N

SMILES: FC=1C=2N(C(=CN2)C3=CC(=C(F)C=C3)C4=C(C#N)C=C(F)C=C4)C=CC1C(C)(C)O

Synonyms:

• 4,2′-Difluoro-5′-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl]biphenyl-2-carbonitrile
• [1,1′-Biphenyl]-2-carbonitrile, 2′,4-difluoro-5′-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl]-
• 2′,4-Difluoro-5′-[8-fluoro-7-(1-hydroxy-1-methylethyl)imidazo[1,2-a]pyridin-3-yl][1,1′-biphenyl]-2-carbonitrile
• TP 003

TP-003

CAS: 628690-75-5

Formula: C₂₃H₁₆F₃N₃O

Purity: 98%

Molecular weight: 407.3878

Ref: IN-DA00EGO0

TP003

CAS: 628690-75-5

TP003

Purity: ≥98%

Molecular weight: 407.39g/mol

Ref: 54-BUP05790

TP 003

CAS: 628690-75-5

Agonist of GABA(A) alpha 3 receptor subunit

Formula: C₂₃H₁₆F₃N₃O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 407.39 g/mol

Ref: 3D-FT103051

TP003

CAS: 628690-75-5

TP003 is a novel non-selective GABAA receptor benzodiazepine site agonist with affinity for α1β2gam2, α2β3gam2, α3β3gam2, α5β2gam2, EC50 of 20.3, 10.6, 3.24, 5.

Formula: C₂₃H₁₆F₃N₃O

Purity: 99.17%

Color and Shape: Solid

Molecular weight: 407.39

Ref: TM-T23466