CAS 6287-83-8

1H-benzimidazole-6-carbonitrile

Description:

1H-benzimidazole-6-carbonitrile is an organic compound characterized by its bicyclic structure, which consists of a benzimidazole ring fused with a cyano group at the 6-position. This compound typically exhibits a white to off-white crystalline appearance and is known for its relatively high stability under standard conditions. It is soluble in polar organic solvents, which facilitates its use in various chemical reactions and applications. The presence of the cyano group contributes to its reactivity, making it a valuable intermediate in the synthesis of pharmaceuticals and agrochemicals. Additionally, 1H-benzimidazole-6-carbonitrile may exhibit biological activity, including potential antimicrobial or anticancer properties, which has garnered interest in medicinal chemistry. Its molecular structure allows for various functionalization possibilities, enhancing its utility in synthetic organic chemistry. As with many nitrogen-containing heterocycles, it may also participate in hydrogen bonding and other intermolecular interactions, influencing its behavior in different chemical environments.

Formula: C₈H₅N₃

InChI: InChI=1/C8H5N3/c9-4-6-1-2-7-8(3-6)11-5-10-7/h1-3,5H,(H,10,11)

SMILES: c1cc2c(cc1C#N)[nH]cn2

Synonyms:

• 1H-Benzimidazole-5-carbonitrile

Benzimidazole-6-carbonitrile, 97%

CAS: 6287-83-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₅N₃

Purity: 97%

Color and Shape: Red to orange to brown, Powder

Molecular weight: 143.15

Ref: 02-H66623

1H-BENZIMIDAZOLE-5-CARBONITRILE

CAS: 6287-83-8

Formula: C₈H₅N₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 143.1454

Ref: IN-DA00ECA9

1H-Benzimidazole-5-carbonitrile

CAS: 6287-83-8

1H-Benzimidazole-5-carbonitrile

Purity: 99%

Molecular weight: 143.15g/mol

Ref: 54-OR46542

1H-Benzo[d]imidazole-6-carbonitrile

CAS: 6287-83-8

Formula: C₈H₅N₃

Purity: 95%

Color and Shape: Solid

Molecular weight: 143.149

Ref: 10-F234123

1H-Benzimidazole-5-carbonitrile

CAS: 6287-83-8

1H-Benzimidazole-5-carbonitrile is a product that belongs to the group of aminopyridine derivatives and has potent activity in vitro. It can be orally administered and has been shown to have pharmacological properties. 1H-Benzimidazole-5-carbonitrile has been shown to inhibit the biosynthesis of prostaglandin E2 by blocking the conversion of arachidonic acid into PGH2 by inhibiting cyclooxygenase, which is an enzyme necessary for the synthesis of prostaglandins. This drug also inhibits platelet aggregation, which is caused by the release of thromboxane A2 from platelets. 1H-Benzimidazole-5-carbonitrile binds to imidazole rings in proteins and prevents them from forming hydrogen bonds with other amino acids, which disrupts protein folding. X-ray crystallographic studies have been used to optimize this drug for oral administration and

Formula: C₈H₅N₃

Purity: Min. 95%

Molecular weight: 143.15 g/mol

Ref: 3D-GAA28783