CAS 62948-75-8

Uric acid-1,3-15N2

Description:

Uric acid-1,3-15N2 is a nitrogen-labeled derivative of uric acid, which is a purine derivative and a product of purine metabolism in humans and other organisms. This compound is characterized by the incorporation of two stable isotopes of nitrogen (15N) at the 1 and 3 positions of the uric acid molecule, which allows for its use in various biochemical and metabolic studies, particularly in tracing nitrogen metabolism. Uric acid itself is a weak acid with a pKa around 5.4, and it is relatively insoluble in water, leading to its precipitation in certain physiological conditions. The presence of the 15N isotopes can be detected using mass spectrometry or NMR spectroscopy, making it a valuable tool in research related to metabolic pathways, nitrogen cycling, and the study of diseases associated with purine metabolism, such as gout. Additionally, uric acid plays a role as an antioxidant in the body, although elevated levels can lead to health issues.

Formula: C₅H₄N₄O₃

InChI: InChI=1/C5H4N4O3/c10-3-1-2(7-4(11)6-1)8-5(12)9-3/h(H4,6,7,8,9,10,11,12)/i8+1,9+1

Synonyms:

• (1,3-15N2)-7,9-dihydro-1H-purine-2,6,8(3H)-trione
• URIC ACID-1,3-15N2, 99 ATOM % 15N
• URIC ACID (1,3-15N2)
• Uric Acid-[15N2
• 15N Labeled uric acid
• URIC ACID-13-15N2 99%
• 2,6,8-Trihydroxypurine-1,3-15N2
• 7,9-Dihydro-1H-purine-2,6,8(3H)-trione-1,3-15N2
• 7,9-dihydro-3H-purine-2,6,8-trione

Uric acid-15N2

CAS: 62948-75-8

Formula: C₅H₄N₄O₃

Purity: %

Color and Shape: Solid

Molecular weight: 170.0971

Ref: IN-DA00EDOH

Uric acid-15N2

CAS: 62948-75-8

Uric acid-15N2

Purity: 98%

Ref: 54-OR1039776

Uric Acid-1,3-15N2

CAS: 62948-75-8

Applications Uric Acid-1,3-15N2 is the labeled analogue of Uric Acid (U829200), a heterocyclcic compound that is created when purine nucleotides are broken down of by the human body. High blood concetration of Uric Acid is known as hyperuricemia and is often associated with a wide range of disorders and medical conditions such as gout, diabetes and metabolic syndrome. Uric acid may be a marker of oxidative stress and may have a potential therapeutic role as an antioxidant.
References Heinig, M. et al.: Cle. Clin. J. Med., 73, 1059 (2006); Glantzounis, G.K. et al.: Curr. Pharmac. Des., 11, 4145 (2005); Dehghan, A. et al.: Diab. Care, 31, 361 (2008); Nakagawa, T. et al.: Am. J. Physiol. Renal Physiol., 290, F625 (2006)

Formula: C₅H₄₁₅N₂N₂O₃

Color and Shape: Neat

Molecular weight: 170.10

Ref: TR-U829203