CAS 62965-35-9

boc-L-tert-leucine

Description:

Boc-L-tert-leucine, with the CAS number 62965-35-9, is a protected form of the amino acid leucine, specifically designed for use in peptide synthesis. The "Boc" (tert-butyloxycarbonyl) group serves as a protective group that prevents unwanted reactions during the synthesis process, allowing for selective modifications of the amino acid. This compound is characterized by its hydrophobic nature due to the bulky tert-butyl group, which influences its solubility and interaction with other molecules. Boc-L-tert-leucine is typically a white to off-white crystalline solid and is soluble in organic solvents like dichloromethane and dimethylformamide, but less soluble in water. It is commonly used in the pharmaceutical and biochemistry fields for the synthesis of peptides and other complex molecules, facilitating the introduction of leucine residues into larger structures. The stability of the Boc group under various conditions makes it a valuable tool in organic synthesis, particularly in the context of solid-phase peptide synthesis.

Formula: C₁₁H₂₁NO₄

InChI: InChI=1/C11H21NO4/c1-10(2,3)7(8(13)14)12-9(15)16-11(4,5)6/h7H,1-6H3,(H,12,15)(H,13,14)/p-1/t7-/m1/s1

InChI key: InChIKey=LRFZIPCTFBPFLX-SSDOTTSWSA-N

SMILES: [C@H](NC(OC(C)(C)C)=O)(C(C)(C)C)C(O)=O

Synonyms:

• (2S)-2-(tert-Butoxycarbonylamino)-3,3-dimethylbutanoic acid
• (2S)-2-[(tert-butoxycarbonyl)amino]-3,3-dimethylbutanoate
• (S)-2-(((tert-Butoxy)carbonyl)amino)-3,3-dimethylbutanoic acid
• (S)-2-tert-Butoxycarbonylamino-3,3-dimethylbutyric acid
• (S)-N-(t-butoxycarbonylamino)-t-leucine
• (S)-N-Boc-t-leucine
• <span class="text-smallcaps">L</span>-Boc-tert-leucine
• <span class="text-smallcaps">L</span>-Valine, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-
• Boc-Leu-OH
• Boc-Tle-OH
• Boc-tBu-Gly-OH
• L-Valine, N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-
• N-(tert-Butoxycarbonyl)-L-leucine
• N-BOC-L-tert-Leucine
• N-Boc-<span class="text-smallcaps">L</span>-tert-leucine
• N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-<span class="text-smallcaps">L</span>-valine
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-tert-butylglycine
• N-tert-Butoxycarbonyl-<span class="text-smallcaps">L</span>-tert-leucine
• NALPHA-tert-Butoxycarbonyl-L-tert-leucine
• N-tert-Butoxycarbonyl-L-tert-leucine
• N-[(1,1-Dimethylethoxy)carbonyl]-3-methyl-L-valine
• BOC-L-TERT-LEUCINE
• BOC-L-ALPHA-T-BUTYLGLYCINE
• BOC-TBU-GLYCINE
• BOC-ALPHA-T-BUTYLGLYCINE
• BOC-ALPHA-BUTYLGLYCINE
• BOC-TLE
• N-ALPHA-T-BUTOXYCARBONYL-L-T-LEUCINE
• N-ALPHA-T-BOC-L-ALPHA-T-BUTYL-GLYCINE
• N-ALPHA-T-BUTYLOXYCARBONYL-L-T-LEUCINE
• N-ALPHA-T-BUTOXYCARBONYL-L-ALPHA-T-BUTYL-GLYCINE
• N-ALPHA-T-BOC-L-T-LEUCINE
• N-ALPHA-TERT-BUTYLOXYCARBONYL-L-TERT-BUTYLGLYCINE
• BOC-ALPHA-T-BUTYL-GLY-OH
• N-ALPHA-T-BUTOXYCARBONYL-(S)-2-AMINO-3,3-DIMETHYL-BUTYRIC ACID
• BOC-L-TLE-OH
• BOC-ALPHA-T-BUTYLGLYCINE-OH
• N-ALPHA-T-BUTOXYCARBONYL-L-T-BUTYLGLYCINE

N-(tert-Butoxycarbonyl)-L-tert-leucine

CAS: 62965-35-9

Formula: C₁₁H₂₁NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 231.29

Ref: 3B-B3754

N-Boc-L-tert-leucine, 98%

CAS: 62965-35-9

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₁H₂₁NO₄

Purity: 98%

Color and Shape: White to pale yellow, Powder or crystals or crystalline powder

Molecular weight: 231.29

Ref: 02-H51136

Boc-Tle-OH

CAS: 62965-35-9

Formula: C₁₁H₂₁NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 231.2887

Ref: IN-DA00IB4A

(2S)-2-(tert-Butoxycarbonylamino)-3,3-dimethyl-butanoic acid

CAS: 62965-35-9

(2S)-2-(tert-Butoxycarbonylamino)-3,3-dimethyl-butanoic acid

Formula: C₁₁H₂₁NO₄

Purity: 98%

Color and Shape: white powder

Molecular weight: 231.28873g/mol

Ref: 54-OR480602

Boc-Tle-OH

CAS: 62965-35-9

Formula: C₁₁H₂₁NO₄

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 231.29

Ref: 7W-GM5211

N-Boc-L-tert-leucine

CAS: 62965-35-9

Formula: C₁₁H₂₁NO₄

Purity: 97%

Color and Shape: Solid, White to Off-White to Light Yellow to Light Beige

Molecular weight: 231.292

Ref: 10-F037101

N-Boc-L-tert-leucine

CAS: 62965-35-9

N-Boc-L-tert-leucine is a β-amino acid that is used as an inhibitor in profiling. It has been shown to inhibit the activity of NS3 protease, which is involved in the synthesis of proteins, and to reduce the production of proinflammatory cytokines. N-Boc-L-tert-leucine has been found to be potent inhibitors of T cell leukemia cells, which may be due to its ability to inhibit protein synthesis. This drug also possesses potential therapeutic effects on metabolic profiles in women.

Formula: C₁₁H₂₁NO₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 231.29 g/mol

Ref: 3D-FA31662

N-tert-Butoxycarbonyl-L-tert-leucine

Controlled Product

CAS: 62965-35-9

Applications Protected amino acid.

Formula: C₁₁H₂₁NO₄

Color and Shape: Neat

Molecular weight: 231.29

Ref: TR-B693480