CAS 629652-72-8
:ent-Tadalafil
Description:
Ent-Tadalafil, with the CAS number 629652-72-8, is a stereoisomer of the well-known phosphodiesterase type 5 (PDE5) inhibitor tadalafil, which is primarily used for the treatment of erectile dysfunction and pulmonary arterial hypertension. As a chemical entity, ent-Tadalafil exhibits similar pharmacological properties to its counterpart, but its specific stereochemistry may influence its binding affinity and efficacy. The compound typically features a bicyclic structure with a pyrimidine ring and a side chain that includes a nitrogen-containing moiety. Its mechanism of action involves the inhibition of PDE5, leading to increased levels of cyclic guanosine monophosphate (cGMP) in the corpus cavernosum, facilitating vasodilation and improved blood flow. The substance is characterized by its relatively high solubility in organic solvents and moderate solubility in water, which can affect its bioavailability. As with other PDE5 inhibitors, ent-Tadalafil may have side effects, including headaches, flushing, and gastrointestinal disturbances, and should be used under medical supervision.
Formula:C22H19N3O4
Synonyms:- (6S,12aS)-tadalafil
- L-Tadalafil
- Unii-Hz6Qjn0D4Z
- L-Tildenafil
- ent-Tadalafil
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Found 10 products.
Tadalafil Enantiomer ((6S,12aS)-6-(1,3-Benzodioxol-5-yl)-2,3,6,7,12,12a-hexahydro-2-methyl-pyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione)
CAS:Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoiFormula:C22H19N3O4Molecular weight:389.13756Tadalafil EP Impurity B ((6S,12S)-Tadalafil)
CAS:Formula:C22H19N3O4Color and Shape:White To Off-White SolidMolecular weight:389.41(6S,12aS)-6-(1,3-Benzodioxol-5-yl)-2-methyl-2,3,6,7,12,12a-hexahydropyrazino[1',2':1,6]pyrido[3,4-b]indole-1,4-dione ((6S,12aS)-Tadalafil)
CAS:Controlled ProductFormula:C22H19N3O4Color and Shape:NeatMolecular weight:389.40ent-Tadalafil
CAS:Controlled Product<p>Impurity Tadalafil EP Impurity B<br>Applications Tadalafil (T004500) analog. Tadalafil Impurity (6S,12aS)<br>References Daugan, A., et al.: J. Med. Chem., 46, 4533 (2003), Jiang, W., et al.: Bioorg. Med. Chem., 12, 1505 (2004),<br></p>Formula:C22H19N3O4Color and Shape:NeatMolecular weight:389.40Ent-tadalafil
CAS:<p>Ent-tadalafil is a compound that is commonly used in research and development for various purposes. It is an isethionate derivative of tadalafil, a well-known medication used to treat erectile dysfunction. Ent-tadalafil has shown potential as an anticancer agent, and it has been studied for its ability to inhibit the growth of cancer cells. In addition, it has been investigated for its potential use in ocular drug delivery systems due to its ability to penetrate the intraocular tissues effectively. Ent-tadalafil can also be used as a surface treatment agent due to its affinity for silver ions, making it useful in industries such as electronics and coatings. Furthermore, ent-tadalafil has been explored for its interactions with other drugs, including irinotecan, trastuzumab, afatinib, and dopamine. Its unique properties make it a valuable compound in the field of research chemicals and pharmaceutical development.</p>Formula:C22H19N3O4Purity:Min. 95%Color and Shape:White To Off-White SolidMolecular weight:389.4 g/molent-Tadalafil
CAS:ent-Tadalafil (ent-IC-351), compound (6S,12aS), is a inactive cis-enantiomer of compound (6R,12aS).Formula:C22H19N3O4Purity:98%Color and Shape:SolidMolecular weight:389.4
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