CAS 62987-05-7

5-Fluoro-1,3-bis(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione

Description:

5-Fluoro-1,3-bis(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione is a chemical compound characterized by its pyrimidinedione core structure, which features a fluorine substituent at the 5-position and two tetrahydro-2-furanyl groups at the 1 and 3 positions. This compound is notable for its potential biological activity, particularly in medicinal chemistry, where pyrimidine derivatives are often explored for their pharmacological properties. The presence of the fluorine atom can enhance lipophilicity and metabolic stability, making it an interesting candidate for drug development. The tetrahydrofuran moieties contribute to the compound's overall stability and may influence its interaction with biological targets. As with many organic compounds, its solubility, reactivity, and stability can vary based on environmental conditions such as pH and temperature. Safety data and handling precautions should be considered, as with any chemical substance, particularly in laboratory or industrial settings. Overall, this compound exemplifies the complexity and diversity of synthetic organic chemistry.

Formula: C₁₂H₁₅FN₂O₄

InChI: InChI=1/C12H15FN2O4/c13-8-7-14(9-3-1-5-18-9)12(17)15(11(8)16)10-4-2-6-19-10/h7,9-10H,1-6H2

InChI key: InChIKey=FLMBDTNCANYTCP-UHFFFAOYSA-N

SMILES: O=C1N(C(=O)C(F)=CN1C2CCCO2)C3CCCO3

Synonyms:

• 1,3-Bis(2-tetrahydrofuryl)-5-fluorouracil
• 1,3-Bis(Tetrahydro-2-furanyl)-5-fluorouracil
• 1,3-Bis(tetrahydro-2-furanyl)-5-fluoro-2,4-pyrimidinedione
• 2,4(1H,3H)-pyrimidinedione, 5-fluoro-1,3-bis(tetrahydro-2-furanyl)-
• 40497S
• 5-Fluoro-1,3-bis(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione
• 5-Fluoro-1,3-di(tetrahydro-2-furanyl)-2,4(1H,3H)-pyrimidinedione
• FD 1 (antitumor agent)
• N¹,N³-Di(2′-tetrahydrofuryl)-5-fluorouracil
• Tegadifur
• 5-Fluoro-1,3-bis(tetrahydrofuran-2-yl)-1,2,3,4-tetrahydropyrimidine-2,4-dione
• 5-fluoro-1,3-bis(tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione
• 5-Fluoro-1,3-bis(tetrahydrofuran-2-yl)-2,4(1H,3H)-pyrimidinedione
• 1,3-Bis(tetrahydrofuran-2-yl)-5-fluoropyrimidine-2,4(1H,3H)-dione
• Tegafur Impurity 7

FD 1

CAS: 62987-05-7

Formula: C₁₂H₁₅FN₂O₄

Purity: 98%

Molecular weight: 270.2569

Ref: IN-DA00EVPE

Tegadifur

CAS: 62987-05-7

Tegadifur

Purity: ≥98%

Molecular weight: 270.26g/mol

Ref: 54-BUP04606

Tegadifur

CAS: 62987-05-7

Tegadifur (40497S) is an orally available antitumor compound with antimetabolic effects, often used with uracil and in the treatment of rectal adenocarcinoma.

Formula: C₁₂H₁₅FN₂O₄

Purity: 99.74% - >99.99%

Color and Shape: Solid

Molecular weight: 270.26

Ref: TM-T13111