CAS 62996-74-1: Staurosporine

Description: Staurosporine is a potent alkaloid derived from the bacterium Streptomyces staurosporeus, known for its broad-spectrum inhibitory effects on protein kinases. It is characterized by its complex tetracyclic structure, which contributes to its biological activity. Staurosporine exhibits a high affinity for various kinases, including those involved in cell signaling pathways, making it a valuable tool in research for studying cellular processes such as apoptosis and cell proliferation. The compound is typically used in laboratory settings to investigate the mechanisms of cancer and other diseases. Staurosporine is also recognized for its potential therapeutic applications, although its use is limited due to its non-selective nature and associated toxicity. In terms of physical properties, it is a crystalline solid that is soluble in organic solvents but has limited solubility in water. As a research chemical, it is important to handle staurosporine with care, adhering to safety protocols due to its potent biological effects.

Formula: C₂₈H₂₆N₄O₃

InChI: InChI=1S/C28H26N4O3/c1-28-26(34-3)17(29-2)12-20(35-28)31-18-10-6-4-8-14(18)22-23-16(13-30-27(23)33)21-15-9-5-7-11-19(15)32(28)25(21)24(22)31/h4-11,17,20,26,29H,12-13H2,1-3H3,(H,30,33)/t17-,20-,26-,28+/m1/s1

InChI key: InChIKey=HKSZLNNOFSGOKW-FYTWVXJKSA-N

SMILES: O=C1NCC=2C1=C3C4=CC=CC=C4N5C3=C6C2C=7C=CC=CC7N6C8(OC5CC(NC)C8OC)C

Synonyms:

• (5R,6S,7S)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one
• (5R,6S,7S,9S)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one
• (5S,6R,7R,9R)-6-methoxy-5-methyl-7-(methylamino)-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-14-one
• (5S,6R,7R,9R)-6-methoxy-N,5-dimethyl-14-oxo-6,7,8,9,15,16-hexahydro-5H,14H-5,9-epoxy-4b,9a,15-triazadibenzo[b,h]cyclonona[1,2,3,4-jkl]cyclopenta[e]-as-indacen-7-aminium
• (9S,10R,11R,13R)-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3′,2′,1′-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one
• 8,12-Epoxy-1H,8H-2,7b,12a-triazadibenzo(a,g)cyclonona(cde)trinden-1-one, 2,3,9,10,11,12-hexahydro-9-methoxy-8-methyl-10-(methylamino)-, (8alpha,9beta,10beta,12alpha)-(+)-
• 9,13-Epoxy-1H,9H-diindolo(1,2,3-gh:3',2',1'-lm)pyrrolo(3,4-j)(1,7)-benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S-(9alpha,10beta,11beta,13alpha)-
• 9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S,10R,11R,13R)-
• 9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, [9S-(9α,10β,11β,13α)]-
• 9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3′,2′,1′-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, (9S,10R,11R,13R)-
• 9,13-Epoxy-1H,9H-diindolo[1,2,3-gh:3′,2′,1′-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one, 2,3,10,11,12,13-hexahydro-10-methoxy-9-methyl-11-(methylamino)-, [9S-(9α,10β,11β,13α)]-
• Alkaloid AM-2282 from Streptomyces
• Am-2282
• Antibiotic 230
• Antibiotic AM 2282
• Ccris 3272
• Cgp 39360
• Staurosporin
• (+)-Staurosporine
• Staurosporine

Staurosporine

CAS: 62996-74-1

• Formula: C₂₈H₂₆N₄O₃
• Purity: >98.0%(HPLC)
• Color and Shape: White to Light yellow powder to crystal
• Molecular weight: 466.54

Staurosporine, 99+%

CAS: 62996-74-1

Broad spectrum protein kinase inhibitor Staurosporine is used as anti-fungal and anti-hypertensive, which results to …

• Formula: C₂₈H₂₆N₄O₃
• Purity: 99+%
• Color and Shape: Crystalline powder or granular, White to pale cream to yellow
• Molecular weight: 466.54

Staurosporine

CAS: 62996-74-1

• Formula: C₂₈H₂₆N₄O₃
• Purity: 100.0%
• Color and Shape: Yellow powder
• Molecular weight: 466.0

Staurosporine

CAS: 62996-74-1

• Formula: C₂₈H₂₆N₄O₃
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 466.531

Staurosporine

CAS: 62996-74-1

• Formula: C₂₈H₂₆N₄O₃
• Purity: (HPLC) ≥ 98.0%
• Color and Shape: Off-white to yellow solid
• Molecular weight: 466.54

Staurosporine

CAS: 62996-74-1

• Purity: 99.87%
• Molecular weight: 466.53g/mol

Staurosporine, from Streptomyces sp.

CAS: 62996-74-1

• Formula: C₂₈H₂₆N₄O₃
• Purity: By hplc: 99.22% (Typical Value in Batch COA)
• Color and Shape: off-white powder
• Molecular weight: 466.53g/mol

STAUROSPORINE

CAS: 62996-74-1

• Purity: 95%
• Molecular weight: 466.540985107422

Staurosporine

CAS: 62996-74-1

• Formula: C₂₈H₂₆N₄O₃
• Color and Shape: Neat
• Molecular weight: 466.53

Staurosporine, 98%

CAS: 62996-74-1

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. …

• Formula: C₂₈H₂₆N₄O₃
• Purity: 98%
• Color and Shape: White to light yellow to light beige, Powder
• Molecular weight: 466.54

Staurosporine

CAS: 62996-74-1

Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6/15/2/3/3000 nM) …

• Formula: C₂₈H₂₆N₄O₃
• Purity: 99.24% - 99.98%
• Color and Shape: Off-White Powder
• Molecular weight: 466.53

Staurosporine

CAS: 62996-74-1

• Formula: C₂₈H₂₆N₄O₃
• Molecular weight: 466.54

Staurosporine

CAS: 62996-74-1

Inhibitor of protein kinases; induces apoptosis; anti-cancer

• Formula: C₂₈H₂₆N₄O₃
• Purity: Min. 98 Area-%
• Color and Shape: Off-White Powder
• Molecular weight: 466.53 g/mol

Staurosporin

CAS: 62996-74-1

Applications Staurosporine is a protein Kinase C inhibitor that induces apoptosis in many cell types. …

• Formula: C₂₈H₂₆N₄O₃
• Color and Shape: Neat
• Molecular weight: 466.53

Staurosporine

CAS: 62996-74-1

Please enquire for more information about Staurosporine including the price, delivery time and more detailed …

• Formula: C₂₈H₂₆N₄O₃
• Purity: Min. 95%
• Molecular weight: 466.53 g/mol