CAS 63-01-4

16α-Hydroxytestosterone

Description:

16α-Hydroxytestosterone is a synthetic steroid and a derivative of testosterone, characterized by the presence of a hydroxyl group at the 16α position of the steroid nucleus. It is classified as an anabolic androgenic steroid (AAS) and is known for its potential to promote muscle growth and enhance physical performance. The compound exhibits both androgenic and anabolic properties, making it of interest in both medical and athletic contexts. In terms of its chemical structure, it retains the core steroid framework, which consists of four fused carbon rings, and its molecular formula reflects the modifications that confer its unique properties. 16α-Hydroxytestosterone is often studied for its effects on protein metabolism and its potential therapeutic applications, although its use in sports is banned by many athletic organizations due to its performance-enhancing effects. As with other steroids, it may also have side effects, including hormonal imbalances and cardiovascular risks, necessitating careful consideration in its use and regulation.

Formula: C₁₉H₂₈O₃

InChI: InChI=1S/C19H28O3/c1-18-7-5-12(20)9-11(18)3-4-13-14(18)6-8-19(2)15(13)10-16(21)17(19)22/h9,13-17,21-22H,3-8,10H2,1-2H3/t13-,14+,15+,16-,17+,18+,19+/m1/s1

InChI key: InChIKey=YMCWOAZGWMZGQT-FPNLOETNSA-N

SMILES: C[C@@]12[C@@]3([C@]([C@]4([C@](C)(CC3)[C@@H](O)[C@H](O)C4)[H])(CCC1=CC(=O)CC2)[H])[H]

Synonyms:

• (16Alpha,17Beta)-16,17-Dihydroxyandrost-4-En-3-One
• (16α,17β)-16,17-Dihydroxyandrost-4-en-3-one
• 16,17-Dihydroxyandrost-4-En-3-One
• 16-Hydroxytestosterone
• 16alpha-Hydroxytestosterone
• 16α,17β-Dihydroxy-4-androsten-3-one
• 16α-Hydroxytestosterone
• 4-Androstene-16α,17β-diol-3-one
• Androst-4-en-3-one, 16,17-dihydroxy-, (16alpha,17beta)- (9CI)
• Androst-4-en-3-one, 16,17-dihydroxy-, (16α,17β)-
• Androst-4-en-3-one, 16α,17β-dihydroxy-

16a-Hydroxytestosterone

Controlled Product

CAS: 63-01-4

Formula: C₁₉H₂₈O₃

Color and Shape: Neat

Molecular weight: 304.424

Ref: TR-H956710

16α-Hydroxytestosterone

Controlled Product

CAS: 63-01-4

16α-Hydroxytestosterone is a metabolite of testosterone that is formed from the oxidation of this hormone by cytochrome P450 enzymes. It has been shown to inhibit the activity of various enzymes, such as NADPH-cytochrome P450 reductase, NADH-cytochrome P450 reductase, and CD-1 mice liver microsomal epoxide hydrolases. This metabolite has been found in experimental models to cause cancerous tumors in rats, and it can also be used to generate monoclonal antibodies against these enzymes. 16α-Hydroxytestosterone binds reversibly to enzymes such as NADP+-dependent dehydrogenases and hydroxylases. The reaction mechanism for this binding involves a dinucleotide phosphate intermediate and anhydrous sodium.

Formula: C₁₉H₂₈O₃

Purity: Min. 98 Area-%

Molecular weight: 304.4 g/mol

Ref: 3D-AAA06301