CAS 63-89-8

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

Description:

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) is a phospholipid commonly used in biochemistry and biophysics, particularly in studies involving cell membranes and liposomes. It is characterized by its two palmitic acid chains, which are saturated fatty acids, contributing to its structural stability and rigidity at physiological temperatures. DPPC has a glycerol backbone with a phosphate group attached to the third carbon, which is further linked to a choline moiety, making it a zwitterionic molecule. This unique structure allows DPPC to form bilayers in aqueous environments, mimicking biological membranes. It exhibits a phase transition temperature, below which it is in a gel state and above which it transitions to a fluid state, influencing membrane fluidity and permeability. DPPC is also utilized in drug delivery systems and as a surfactant in various pharmaceutical formulations due to its ability to stabilize emulsions and enhance the solubility of hydrophobic compounds. Its CAS number is 63-89-8, indicating its unique identification in chemical databases.

Formula: C₄₀H₈₀NO₈P

InChI: InChI=1S/C40H80NO8P/c1-6-8-10-12-14-16-18-20-22-24-26-28-30-32-39(42)46-36-38(37-48-50(44,45)47-35-34-41(3,4)5)49-40(43)33-31-29-27-25-23-21-19-17-15-13-11-9-7-2/h38H,6-37H2,1-5H3/t38-/m1/s1

InChI key: InChIKey=KILNVBDSWZSGLL-KXQOOQHDSA-N

SMILES: [C@H](OC(CCCCCCCCCCCCCCC)=O)(COP(OCC[N+](C)(C)C)(=O)[O-])COC(CCCCCCCCCCCCCCC)=O

Synonyms:

• (2R)-2,3-bis(hexadecanoyloxy)propyl 2-(trimethylammonio)ethyl phosphate
• (R)-(4-Oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium-4-oxid
• (R)-(4-oxido-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium 4-oxide
• (R)-2,3-Bis(palmitoyloxy)propyl (2-(trimethylammonio)ethyl) phosphate
• 1,2-<span class="text-smallcaps">L</span>-α-Dipalmitoylphosphatidylcholine
• 1,2-Bis(hexadecanoyl)-sn-glycero-3-phosphocholine
• 1,2-Bis(palmitoyl)-sn-glycero-3-phosphocholine
• 1,2-Dihexadecanoyl-sn-glycero-3-phophocholine
• 1,2-Dihexadecanoyl-sn-glycero-3-phosphocholine
• 1,2-Dihexadecanoyl-sn-glycero-3-phosphorylcholine
• 1,2-Dihexadecanoyl-sn-glycerol-3-phosphorylcholine
• 1,2-Dipalmitoyl-3-Sn-Phosphatidylcholine
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-3-phosphatidylcholine
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-lecithin
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-phosphatidylcholine
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-α-lecithin
• 1,2-Dipalmitoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• 1,2-Dipalmitoyl-L-3-phosphatidylcholine
• 1,2-Dipalmitoyl-L-lecithin
• 1,2-Dipalmitoyl-L-phosphatidylcholine
• 1,2-Dipalmitoyl-L-α-lecithin
• 1,2-Dipalmitoyl-L-α-phosphatidylcholine
• 1,2-Dipalmitoyl-sn-3-glycerophosphocholine
• 1,2-Dipalmitoyl-sn-glycero-3-phosphatidylcholine
• 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine
• 1,2-Dipalmitoyl-sn-glycero-3-phosphocholine monohydrate
• 1,2-Dipalmitoyl-sn-glycero-3-phosphorylcholine
• 1,2-Dipalmitoyl-sn-glycerol-3-phosphocholine
• 1,2-Dipalmitoyl-sn-glycerophosphocholine
• 1,2-Dipalmitoyl-sn-glycerophosphorylcholine
• 1,2-Dipalmitoyl-sn-glyceryl-3-phosphocholine
• 1,2-Dipalmitoyl-sn-phosphatidylcholine
• 1,2-Dipalmitoylglycero-3-phosphocholine
• 1,2-Dispalmitoyl-sn-phosphatidylcholine
• 1,2-L-α-Dipalmitoylphosphatidylcholine
• 1,2-Palmitoyl-sn-glycero-3-phosphocholine
• 1,2-dipalmitoyl-L-alpha-phosphatidylcholine
• 129Y83
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, hydroxide, inner salt, 4-oxide, (R)-
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (7R)-
• 3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[(1-oxohexadecyl)oxy]-, inner salt, 4-oxide, (R)-
• 4-oxido de (R)-(4-oxido-10-oxo-7-palmitoil-3,5,9-trioxa-4-fosfapentacosil)trimetilamonio
• 4-oxyde de (R)-(4-oxydo-10-oxo-7-palmitoyl-3,5,9-trioxa-4-phosphapentacosyl)trimethylammonium
• 55: PN: WO2017201317 SEQID: 128 claimed RNA
• <span class="text-smallcaps">L</span>-1,2-Dipalmitoyl-α-lecithin
• <span class="text-smallcaps">L</span>-1,2-Dipalmitoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-DPPC
• <span class="text-smallcaps">L</span>-Dipalmitoyl lecithin
• <span class="text-smallcaps">L</span>-Dipalmitoyl phosphatidylcholine
• <span class="text-smallcaps">L</span>-Dipalmitoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-α-1,2-Dipalmitoyl lecithin
• <span class="text-smallcaps">L</span>-α-DPPC
• <span class="text-smallcaps">L</span>-α-Dipalmitoylecithin
• <span class="text-smallcaps">L</span>-α-Dipalmitoyllecithin
• <span class="text-smallcaps">L</span>-α-Dipalmitoylphosphatidylcholine
• <span class="text-smallcaps">L</span>-α-Lecithin
• <span class="text-smallcaps">L</span>-β,γ-Dipalmitoyl-α-lecithin
• <span class="text-smallcaps">L</span>-β,γ-Dipalmitoyl-α-phosphatidylcholine
• <span class="text-smallcaps">L</span>-β,γ-Dipalmitoylphosphatidylcholine
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipalmitin, <span class="text-smallcaps">L</span>-
• Choline, hydroxide, dihydrogen phosphate, inner salt, ester with 1,2-dipalmitin, L-
• Colfosceril Palmitate
• Dihexadecanoyl-sn-glycero-3-phosphocholine
• Dipalmitoyl L-α-phosphatidylcholine
• Dipalmitoyl-<span class="text-smallcaps">L</span>-3-glycerylphosphorylcholine
• Dipalmitoyl-<span class="text-smallcaps">L</span>-lecithin
• Dipalmitoyl-<span class="text-smallcaps">L</span>-α-lecithin
• Dipalmitoyl-<span class="text-smallcaps">L</span>-α-phosphatidylcholine
• Dipalmitoyl-L-3-glycerylphosphorylcholine
• Dipalmitoyl-L-α-lecithin
• Dipalmitoyl-sn-3-phosphatidylcholine
• Dipalmitoyl-sn-glycero-3-phosphocholine
• Dipalmitoylphosphatidylcholine
• Dppc
• L-1,2-Dipalmitoyl-α-lecithin
• L-1,2-Dipalmitoylphosphatidylcholine
• L-A-phosphatidylcholine dipalmitoyl*synthetic
• L-Dipalmitoyl lecithin
• L-Dppc
• L-a-Dipalmitoyl Lecithin
• L-a-Lecitin-dipalmitoyl
• L-α-1,2-Dipalmitoyl lecithin
• L-α-DPPC
• L-α-Dipalmitoylecithin
• L-α-Dipalmitoyllecithin
• L-α-Dipalmitoylphosphatidylcholine
• L-α-Lecithin
• L-β,γ-Dipalmitoyl-α-lecithin
• L-β,γ-Dipalmitoyl-α-phosphatidylcholine
• L-β,γ-Dipalmitoylphosphatidylcholine
• Palmitin, 1,2-di-, dihydrogen phosphate, monoester with choline hydroxide, inner salt, <span class="text-smallcaps">L</span>-
• [(2R)-2,3-Di(hexadecanoyloxy)propyl] 2-(trimethylazaniumyl)ethyl phosphate
• sn-3-Dipalmitoyllecithin
• β,γ-Dipalmitoyl <span class="text-smallcaps">L</span>-α-phosphatidylcholine
• β,γ-Dipalmitoyl L-α-phosphatidylcholine
• β,γ-Dipalmitoyl-<span class="text-smallcaps">L</span>-(α)-lecithin
• β,γ-Dipalmitoyl-<span class="text-smallcaps">L</span>-phosphatidylcholine
• β,γ-Dipalmitoyl-L-(α)-lecithin
• β,γ-Dipalmitoyl-L-phosphatidylcholine

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

Formula: C₄₀H₈₀NO₈P

Purity: >98.0%(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 734.05

Ref: 3B-D3925

DPPC

CAS: 63-89-8

Purity: 97%

Molecular weight: 734.052978515625

Ref: 10-F601359

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

Bachem ID: 4004249.

Formula: C₄₀H₈₀NO₈P

Purity: > 99%

Color and Shape: White Powder

Molecular weight: 734.05

Ref: 01-4004249

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

Formula: C₄₀H₈₀NO₈P

Purity: By hplc: 98% (Typical Value in Batch COA)

Color and Shape: white solid

Molecular weight: 734.04g/mol

Ref: 54-BIB6043

DPPC

CAS: 63-89-8

DPPC

Purity: ≥98%

Molecular weight: 734.04g/mol

Ref: 54-BUP15935

DPPC (Dipalmitoylphosphatidylcholine)

CAS: 63-89-8

Formula: C₄₀H₈₀NO₈P

Color and Shape: White To Off-White Solid

Molecular weight: 734.05

Ref: 4Z-C-594

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

Formula: C₄₀H₈₀NO₈P

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 734.04

Ref: 7W-GL3400

1,2-Dipalmitoyl-sn-Glycero-3-Phosphatidylcholine

CAS: 63-89-8

Formula: C40H80NO8P

Purity: >99%

Color and Shape: Solid

Molecular weight: 734.04

Ref: 48-37-1600

Succinyl Monocholine Chloride-d4

CAS: 63-89-8

Formula: C₉H₁₄D₄ClNO₄

Color and Shape: White To Off-White Solid

Molecular weight: 243.72

Ref: 4Z-C-5947

DPPC

CAS: 63-89-8

DPPC (129Y83) is a zwitterionic glycerophospholipid commonly used in the formation of lipid monolayers, bilayers, and liposomes.

Formula: C₄₀H₈₀NO₈P

Purity: 99.33% - 99.5%

Color and Shape: Solid

Molecular weight: 734.04

Ref: TM-T7773

1,​2-​Dipalmitoyl-​sn-​glycero-​3-​phosphocholine (Colfosceril Palmitate)

Controlled Product

CAS: 63-89-8

Stability Hygroscopic
Applications Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
References Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998), Pantusa, M., et al.: Biophys Chem., 114, 121 (2005), Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008), Lautenslager, G., et al.: Metabolism, 60, 1683 (2011),

Formula: C₄₀H₈₀NO₈P

Color and Shape: Neat

Molecular weight: 734.04

Ref: TR-C640500

Colfosceril-d9 Palmitate

Controlled Product

CAS: 63-89-8

Applications Labelled Colfosceril Palmitate (C640500). Colfosceril Palmitate is a major phospholipid constituent and primary surface tension lowering component of natural lung surfactant. Colfosceril Palmitate is used as pulmonary surfactant and diagnostic aid (fetal lung maturity).
References Cha, S., et al.: J. Biol. Chem., 273, 2153 (1998), Pantusa, M., et al.: Biophys Chem., 114, 121 (2005), Pantusa, M., et al.: Eur. Biophys. J., 37, 961 (2008), Lautenslager, G., et al.: Metabolism, 60, 1683 (2011),

Formula: C₄₀D₉H₇₁NO₈P

Color and Shape: Neat

Molecular weight: 743.094

Ref: TR-C640502

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine

CAS: 63-89-8

1,2-Dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) is a sodium salt that has the ability to form surfactant bilayers. DPPC is a model system for studying biochemical reactions and the phase transition of lipid bilayers. This compound has been used to study the effects of various drugs on cell membranes in biochemical research. In addition, DPPC has been shown to have hypoglycemic effects in animal models as well as having an anti-inflammatory effect.

Formula: C₄₀H₈₀NO₈P

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 734.04 g/mol

Ref: 3D-FD46765