CAS 630-94-4

Corynoxeine

Description:

Corynoxeine is a naturally occurring alkaloid primarily derived from the plant species of the genus Uncaria, commonly known as cat's claw. It is characterized by its complex molecular structure, which includes multiple rings and functional groups that contribute to its biological activity. Corynoxeine exhibits a range of pharmacological properties, including anti-inflammatory, analgesic, and neuroprotective effects, making it of interest in medicinal chemistry and pharmacology. The compound has been studied for its potential therapeutic applications, particularly in the treatment of neurodegenerative diseases and pain management. Additionally, Corynoxeine has shown antioxidant properties, which may help in combating oxidative stress in biological systems. Its mechanism of action involves modulation of various signaling pathways, although further research is needed to fully elucidate its effects and potential clinical applications. As with many natural products, the extraction and purification of Corynoxeine can be challenging, and its stability under different conditions is an important consideration for its use in research and therapeutic contexts.

Formula: C₂₂H₂₆N₂O₄

InChI: InChI=1S/C22H26N2O4/c1-4-14-12-24-10-9-22(17-7-5-6-8-18(17)23-21(22)26)19(24)11-15(14)16(13-27-2)20(25)28-3/h4-8,13-15,19H,1,9-12H2,2-3H3,(H,23,26)/b16-13+/t14-,15-,19-,22+/m0/s1

InChI key: InChIKey=MUVGVMUWMAGNSY-KAXDATADSA-N

SMILES: O=C1[C@@]2([C@]3(N(CC2)C[C@H](C=C)[C@@H](\C(\C(OC)=O)=C/OC)C3)[H])C=4C(N1)=CC=CC4

Synonyms:

• Corynoxan-16-carboxylic acid, 16,17,18,19-tetradehydro-17-methoxy-2-oxo-, methyl ester, (7β,16E,20α)-
• Corynoxein
• Isocorynoxeine
• Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethenyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, (αE,1′R,6′R,7′S,8′aS)-
• Spiro[3H-indole-3,1′(5′H)-indolizine]-7′-acetic acid, 6′-ethenyl-1,2,2′,3′,6′,7′,8′,8′a-octahydro-α-(methoxymethylene)-2-oxo-, methyl ester, [1′R-[1′α,6′β,7′α(E),8′aβ]]-
• methyl (16E,20alpha)-16-(methoxymethylidene)-2-oxocorynox-18-en-17-oate
• Δ¹⁸-Rhyncophylline
• δ¹⁸-Rhynchophylline
• Δ18-Rhyncophylline
• Corynoxeine

Corynoxeine

CAS: 630-94-4

Formula: C₂₂H₂₆N₂O₄

Purity: 96%

Color and Shape: Solid

Molecular weight: 382.4528

Ref: IN-DA00EBHB

Corynoxeine

CAS: 630-94-4

Formula: C₂₂H₂₆N₂O₄

Molecular weight: 382.46

Ref: 7W-GY1272

Corynoxeine

CAS: 630-94-4

Corynoxeine

Purity: ≥98%

Molecular weight: 382.45g/mol

Ref: 54-BUP07805

Corynoxeine

CAS: 630-94-4

Formula: C₂₂H₂₆N₂O₄

Purity: 95%~99%

Molecular weight: 382.46

Ref: BP-BP0399

Corynoxeine

CAS: 630-94-4

Corynoxeine

Molecular weight: 382.45g/mol

Ref: 54-BISN0234

Corynoxeine

CAS: 630-94-4

Corynoxeine inhibits ERK1/2, curbs VSMC growth induced by PDGF-BB, and may prevent vascular diseases and restenosis post-angioplasty.

Formula: C₂₂H₂₆N₂O₄

Purity: 98.61% - 99.94%

Color and Shape: Solid

Molecular weight: 382.45

Ref: TM-T6S0655

corynoxeine

CAS: 630-94-4

Corynoxeine is a type of matrix effect and is found in the rhizome of uncaria, which is a Chinese herb. It has been shown to have synergic effects with alkaloids, such as isocorynoxeine, and the extract has been shown to be an effective treatment for inflammatory skin diseases. Corynoxeine also has anti-inflammatory and anticancer activities. The optimal extraction process for corynoxeine involves extracting the rhizomes with ethanol at low temperature.

Purity: Min. 95%

Ref: 3D-FC73948