CAS 630125-91-6

Benzenamine, 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-

Description:

Benzenamine, 4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-, also known by its CAS number 630125-91-6, is an organic compound characterized by its aromatic amine structure. It features a benzene ring substituted with a trifluoromethyl group and a piperazine moiety, which contributes to its potential biological activity. The presence of the trifluoromethyl group enhances lipophilicity and may influence the compound's pharmacokinetic properties. The piperazine ring, known for its role in various pharmaceuticals, adds to the compound's ability to interact with biological targets. This compound may exhibit properties such as moderate to high solubility in organic solvents and limited solubility in water, typical of many aromatic amines. Its structure suggests potential applications in medicinal chemistry, particularly in the development of new therapeutic agents. However, specific safety and handling guidelines should be followed due to the presence of the amine functional group, which can be reactive. Overall, this compound represents a class of substances with significant interest in drug discovery and development.

Formula: C₁₄H₂₀F₃N₃

4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

CAS: 630125-91-6

Formula: C₁₄H₂₀F₃N₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 287.3239

Ref: IN-DA00ECCF

4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

CAS: 630125-91-6

4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

Purity: 98%

Molecular weight: 287.329g/mol

Ref: 54-PC99861

4-((4-Ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)aniline

CAS: 630125-91-6

Formula: C₁₄H₂₀F₃N₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 287.33

Ref: 10-F420335

4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine

Controlled Product

CAS: 630125-91-6

Applications 4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)-benzenamine is one of the key reactants with N-[1-(4-Aminophenyl)-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide used in the synthesis of a pyrrolo[3,2-c]pyridine derivative [N-[1-[4-[[[[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-1H-pyrrolo[3,2-c]pyridin-4-yl]benzamide (I)], an anticancer diarylurea derivative with multiple-kinase inhibitory effect; Also, it is an intermediate used in the synthesis of N-[4-[(4-Ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-N'-[4-[[6-(methylamino)-4-pyrimidinyl]oxy]phenyl]urea (E926495), which is an inhibitor of RET, FLT3, KDR, c-Abl and c-Kit. Also, it prevent the growth of human thyroid cancer cells.
References El-Gamal, M. I., et al.: Bull. Korean Chem. Soc., 33, 1571-1576 (2012); Weisberg, E., et al.: Genes Cancer, 1, 1021-1032 (2010);

Formula: C₁₄H₂₀F₃N₃

Color and Shape: Neat

Molecular weight: 287.324

Ref: TR-E924295