CAS 6304-16-1

4-Pyridylacetone

Description:

4-Pyridylacetone, with the CAS number 6304-16-1, is an organic compound characterized by its pyridine ring and an acetone functional group. It typically appears as a yellow to brown liquid or solid, depending on its purity and form. The compound features a pyridine moiety, which contributes to its aromatic properties and potential for hydrogen bonding. 4-Pyridylacetone is known for its ability to chelate metal ions, making it useful in coordination chemistry and as a ligand in various applications. It has a moderate solubility in polar solvents like water and alcohols, while being less soluble in non-polar solvents. The compound exhibits a range of chemical reactivity, including potential for oxidation and substitution reactions. Its applications span across fields such as pharmaceuticals, where it may serve as an intermediate in the synthesis of various bioactive compounds, and in materials science for the development of functional materials. Safety precautions should be taken when handling this compound, as it may pose health risks upon exposure.

Formula: C₈H₉NO

InChI: InChI=1/C8H9NO/c1-7(10)6-8-2-4-9-5-3-8/h2-5H,6H2,1H3

InChI key: InChIKey=ILRVKOYYFFNXDB-UHFFFAOYSA-N

SMILES: C(C(C)=O)C=1C=CN=CC1

Synonyms:

• 1-(4-Pyridinyl)-2-propanone
• 1-(4-Pyridyl)-2-acetone
• 1-(4-Pyridyl)-2-propanone
• 1-(4-Pyridyl)acetone
• 1-(Pyridin-4-Yl)Propan-2-One
• 1-(Pyridin-4-yl)acetone
• 2-Propanone, (4-pyridyl)-
• 2-Propanone, 1-(4-pyridinyl)-
• 2-Propanone, 1-(4-pyridyl)-
• 4-(2-Oxopropyl)pyridine
• 4-Acetonylpyridine
• 4-Pyridinylacetone
• 4-Pyridylacetone
• Methyl 4-pyridylmethyl ketone
• NSC 42613
• 4-Pyridyl acetone
• (4-PYRIDINEYL)-ACETONE
• 1-(4-Pyridinyl)-2-propanone CAS:
• 4-Pyridinolacetone
• (PYRIDIN-4-YL)ACETONE

(4-Pyridyl)acetone

CAS: 6304-16-1

Formula: C₈H₉NO

Purity: 96%

Color and Shape: Liquid

Molecular weight: 135.1632

Ref: IN-DA003M0N

(Pyridin-4-yl)acetone

CAS: 6304-16-1

(Pyridin-4-yl)acetone

Formula: C₈H₉NO

Purity: 98%

Color and Shape: clear. dark orange liquid

Molecular weight: 135.16316g/mol

Ref: 54-OR9025

(4-Pyridyl)acetone

CAS: 6304-16-1

(4-Pyridyl)acetone is a pyridine derivative widely used in biochemical experiments and drug synthesis research.

Formula: C₈H₉NO

Purity: 98.22%

Color and Shape: Solid

Molecular weight: 135.16

Ref: TM-TN9317

(4-Pyridyl)acetone

Controlled Product

CAS: 6304-16-1

Applications (4-Pyridyl)acetone is a reactant in the synthesis of Milrinone (M344680), a selective phosphodiesterase inhibitor with vasodilating and positive inotropic activity. Cardiotonic.
References Singh, B.: Heterocycles, 23, 1479 (1985); Alousi, A.A., et al.: J. Cardiovasc Pharmacol., 5, 792 (1983); Maskin, C.S., et al.: Circulation, 67, 1065 (1983); Sinoway, L.S., et al.: J. Am. Coll. Cardiol., 2, 327 (1983); Baim, D.S., et al.: N. Engl. J. Med., 309, 748 (1983)

Formula: C₈H₉NO

Color and Shape: Neat

Molecular weight: 135.16

Ref: TR-P991845

(4-Pyridyl)acetone

CAS: 6304-16-1

4-Pyridylacetone (4PA) is a chloride channel blocker that blocks the ion channels in muscle cells, leading to decreased levels of chloride ions. This leads to the inhibition of the release of pro-inflammatory cytokines and therefore has potential as a treatment for inflammatory diseases such as congestive heart failure, chronic obstructive pulmonary disease, and atherosclerosis. 4PA also inhibits the activation of macrophages by LPS, which may be beneficial in treating autoimmune disorders. Molecular docking analysis has shown that 4PA can bind to aminomalonamide, a drug used to treat myeloma cancer, suggesting that it could be used as an alternative treatment.

Formula: C₈H₉NO

Purity: Min. 98 Area-%

Color and Shape: Colorless Yellow Clear Liquid

Molecular weight: 135.16 g/mol

Ref: 3D-FP36055

(4-Pyridyl)acetone

CAS: 6304-16-1

Formula: C₈H₉NO

Purity: 96%

Color and Shape: Liquid

Molecular weight: 135.166

Ref: 10-F068404

Milrinone Impurity 20

CAS: 6304-16-1

Formula: C₈H₉NO

Molecular weight: 135.17

Ref: ST-EA-CP-M48013