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CAS 6306-71-4

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Lobendazole

Description:
Lobendazole is an anthelmintic agent primarily used in veterinary medicine for the treatment of parasitic infections in livestock. It belongs to the benzimidazole class of compounds, which are known for their ability to inhibit the polymerization of tubulin, thereby disrupting the cytoskeleton of parasitic worms. Lobendazole is characterized by its relatively low solubility in water, which affects its bioavailability and absorption in biological systems. The compound is typically administered orally and is effective against a range of nematodes and cestodes. Its mechanism of action involves interfering with the energy metabolism of the parasites, leading to their eventual death. Lobendazole is generally considered to have a favorable safety profile when used as directed, although potential side effects may occur, particularly with overdosing. The compound's efficacy and safety make it a valuable tool in managing parasitic infections in animals, contributing to improved health and productivity in livestock.
Formula:C10H11N3O2
InChI:InChI=1S/C10H11N3O2/c1-2-15-10(14)13-9-11-7-5-3-4-6-8(7)12-9/h3-6H,2H2,1H3,(H2,11,12,13,14)
InChI key:InChIKey=OKOVSTKGUBOSTB-UHFFFAOYSA-N
SMILES:N(C(OCC)=O)C=1NC=2C(N1)=CC=CC2
Synonyms:
  • 2-((Ethoxycarbonyl)amino)benzimidazole
  • 2-Benzimidazolecarbamic acid, ethyl ester
  • 2-Benzimidazolecarbamic acid, ethyl ester (8CI)
  • 2-Carboethoxyaminobenzimidazole
  • Benzimidazol-2-ylcarbamate ethyl ester
  • Benzimidazole carbamate d'ethyle
  • Benzimidazole carbamate d'ethyle [French]
  • Carbamic acid, (2-benzimidazolyl)-, ethyl ester
  • Carbamic acid, 1H-benzimidazol-2-yl-, ethyl ester
  • Carbamic acid, N-1H-benzimidazol-2-yl-, ethyl ester
  • See more synonyms
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