CAS 63069-49-8

2-Amino-5-fluorobenzamide

Description:

2-Amino-5-fluorobenzamide is an organic compound characterized by the presence of an amino group (-NH2) and a fluorine atom attached to a benzene ring, specifically at the 5-position relative to the amide functional group (-C(=O)NH2). This compound is typically a white to off-white solid and is soluble in polar solvents such as water and alcohols, owing to its ability to form hydrogen bonds. The presence of the amino group contributes to its basicity, while the fluorine atom can influence its reactivity and biological activity due to its electronegative nature. 2-Amino-5-fluorobenzamide is of interest in medicinal chemistry and research due to its potential applications in pharmaceuticals, particularly as a building block for the synthesis of various biologically active compounds. Its molecular structure allows for interactions with biological targets, making it a subject of study in drug development and chemical biology. Safety data should be consulted for handling and usage, as with all chemical substances.

Formula: C₇H₇FN₂O

InChI: InChI=1S/C7H7FN2O/c8-4-1-2-6(9)5(3-4)7(10)11/h1-3H,9H2,(H2,10,11)

InChI key: InChIKey=RHJMYIPLYKQZJM-UHFFFAOYSA-N

SMILES: C(N)(=O)C1=C(N)C=CC(F)=C1

Synonyms:

• 5-Fluoro-2-aminobenzamide
• Benzamide,2-amino-5-fluoro-
• 2-Amino-5-fluorobenzamide

2-Amino-5-fluorobenzamide

CAS: 63069-49-8

Formula: C₇H₇FN₂O

Purity: >98.0%(HPLC)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 154.14

Ref: 3B-A3181

2-AMINO-5-FLUOROBENZAMIDE

CAS: 63069-49-8

Formula: C₇H₇FN₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 154.1417

Ref: IN-DA0036Z8

2-Amino-5-fluorobenzamide

CAS: 63069-49-8

2-Amino-5-fluorobenzamide

Formula: C₇H₇FN₂O

Purity: 97%

Color and Shape: White To Off White Powder

Molecular weight: 154.14g/mol

Ref: 54-PC1994

2-Amino-5-fluorobenzamide

CAS: 63069-49-8

Formula: C₇H₇FN₂O

Purity: 95%

Color and Shape: Solid

Molecular weight: 154.144

Ref: 10-F061688

2-Amino-5-fluorobenzamide

CAS: 63069-49-8

2-Amino-5-fluorobenzamide (2AFB) is a compound that has been shown to have neurotoxic properties. 2AFB is a ring-opening agent, which means it can open the six-membered ring of aromatic compounds such as benzene or pyridine. 2AFB also has affinity for metal ions and therefore can be used in magnetic separations. The reaction system of 2AFB includes an enzyme, pentylenetetrazole (PTZ), that catalyzes the reaction between 2AFB and its substrate, 4-nitrophenol (4NP). This reaction produces free radicals that react with oxygen to produce peroxides. These peroxides are then detected by a chemiluminescence assay. In this way, the amount of 2AFB and 4NP can be measured quantitatively.
2AFB also has antioxidant properties, which may be due to its ability to scavenge free radicals from

Formula: C₇H₇FN₂O

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 154.14 g/mol

Ref: 3D-FA70235