CAS 63121-00-6: (SP-4-2)-[rel-(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]platinum

Description: The chemical substance known as (SP-4-2)-[rel-(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]platinum, with the CAS number 63121-00-6, is a platinum complex that features a chiral cyclohexanediamine ligand coordinated to a platinum center. This compound exhibits characteristics typical of platinum(II) complexes, including potential applications in medicinal chemistry, particularly in cancer treatment due to its ability to interact with DNA. The presence of the cyclohexanediamine ligand contributes to its stereochemistry, which can influence its biological activity and interaction with cellular targets. The ethanedioate (oxalate) ligands provide additional stability and can enhance solubility in biological systems. Overall, this compound's unique structural features and coordination environment make it a subject of interest in coordination chemistry and pharmacology, particularly in the development of novel therapeutic agents. Its properties, such as solubility, reactivity, and biological activity, are influenced by its specific ligand arrangement and the oxidation state of the platinum center.

Formula: C₈H₁₄N₂O₄Pt

InChI: InChI=1/C6H14N2.C2H2O4.Pt/c7-5-3-1-2-4-6(5)8;3-1(4)2(5)6;/h5-6H,1-4,7-8H2;(H,3,4)(H,5,6);/q;;+2/p-2/t5-,6-;;/s2

InChI key: InChIKey=ZROHGHOFXNOHSO-WHMNLBETNA-L

SMILES: O=C1[O-][Pt+2]2([O-]C1=O)[NH2]C3CCCCC3[NH2]2

Synonyms:

• (1R,2R)-cyclohexane-1,2-diamine: oxalic acid: platinum(+2) cation
• (SP-4-2)-[rel-(1R,2R)-1,2-Cyclohexanediamine-κN¹,κN²][ethanedioato(2-)-κO¹,κO²]platinum
• (sp-4-2)-((1r,2r)-1,2-cyclohexanediamine-n,n')(ethanedioato(2-)-O,O']platinum
• 1,2-Cyclohexanediamine, platinum complex, trans-
• Act 078
• Cyclohexane-1,2-Diamine: Oxalic Acid: Platinum
• Elocatin
• Latin
• NSC 271670
• Nsc-266046
• Oxalato(trans-(-)-1,2-cyclohexanediamine)platinum(II)
• Oxalipatin
• Platinum(4+) Cyclohexane-1,2-Diyldiazanide Ethanedioate (1:1:1)
• Platinum, (1,2-cyclohexanediamine-N,N′)[ethanedioato(2-)-O,O′]-, [SP-4-2-(trans)]-
• Platinum, [rel-(1R,2R)-1,2-cyclohexanediamine-κN,κN′][ethanedioato(2-)-κO¹,κO²]-, (SP-4-2)-
• Platinum, [rel-(1R,2R)-1,2-cyclohexanediamine-κN¹,κN²][ethanedioato(2-)-κO¹,κO²]-, (SP-4-2)-
• Rp-54780
• Xalatoplatinum
• [SP-4-2-(IR-trans)]-(1,2-cyclohexanediamine-n,n')[ethanedioato(2-)-O,O']-platinum
• platinum(2+) ethanedioate (1R,2R)-cyclohexane-1,2-diamine (1:1)
• trans-L-Diaminocyclohexane oxalatoplatinum
• ι-OHP
• Platinum, [rel-(1R,2R)-1,2-cyclohexanediamine-κN,κN′][ethanedioato(2-)-κO1,κO2]-, (SP-4-2)-
• Platinum, [rel-(1R,2R)-1,2-cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]-, (SP-4-2)-
• (SP-4-2)-[rel-(1R,2R)-1,2-Cyclohexanediamine-κN1,κN2][ethanedioato(2-)-κO1,κO2]platinum

Oxaliplatin

CAS: 63121-00-6

• Purity: ≥95%
• Molecular weight: 397.289g/mol

Oxaliplatin-d10

CAS: 63121-00-6

• Formula: C₈H₂D₁₀N₂O₄Pt
• Molecular weight: 405.34

(rel)-Oxaliplatin

CAS: 63121-00-6

(rel)-Oxaliplatin, a DNA inhibitor, induces crosslinks, hinders replication/transcription, and triggers apoptosis; used in cancer studies.

• Formula: C₈H₁₄N₂O₄Pt
• Color and Shape: Solid
• Molecular weight: 397.29