CAS 63132-39-8

Olpadronic acid

Description:

Olpadronic acid, with the CAS number 63132-39-8, is a bisphosphonate compound primarily used in the treatment of bone-related disorders, particularly osteoporosis and Paget's disease. It functions by inhibiting osteoclast-mediated bone resorption, thereby helping to maintain or increase bone density. The chemical structure of olpadronic acid features two phosphonate groups, which are responsible for its strong affinity for hydroxyapatite in bone tissue. This compound is typically administered orally and is characterized by its relatively low solubility in water, which influences its bioavailability. In terms of safety, olpadronic acid has been evaluated for its potential side effects, which may include gastrointestinal disturbances and, in rare cases, osteonecrosis of the jaw. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are crucial for its therapeutic efficacy. Overall, olpadronic acid represents an important therapeutic option in managing conditions associated with bone loss.

Formula: C₅H₁₅NO₇P₂

InChI: InChI=1S/C5H15NO7P2/c1-6(2)4-3-5(7,14(8,9)10)15(11,12)13/h7H,3-4H2,1-2H3,(H2,8,9,10)(H2,11,12,13)

InChI key: InChIKey=UGEPSJNLORCRBO-UHFFFAOYSA-N

SMILES: C(P(=O)(O)O)(P(=O)(O)O)(CCN(C)C)O

Synonyms:

• 3-(Dimethylamino)-1-hydroxypropylidene-1,1-bisphosphonic acid
• 3-Dimethylamino-1-hydroxypropane-1,1-diphosphonic acid
• 3-Dimethylamino-1-hydroxypropylidenebiphosphonic acid
• 63132-39-8
• Olpadronic acid
• P,P′-[3-(Dimethylamino)-1-hydroxypropylidene]bis[phosphonic acid]
• Phosphonic acid, P,P′-[3-(dimethylamino)-1-hydroxypropylidene]bis-
• Phosphonic acid, [3-(dimethylamino)-1-hydroxypropylidene]bis-
• [3-(Dimethylamino)-1-hydroxy-1-phosphonopropyl]phosphonic acid
• [3-(Dimethylamino)-1-hydroxypropane-1,1-diyl]bis(phosphonic acid)

Olpadronic acid

CAS: 63132-39-8

Olpadronic acid is a biochemical.

Formula: C₅H₁₅NO₇P₂

Color and Shape: Solid

Molecular weight: 263.12

Ref: TM-T33793

Ibandronate Sodium Impurity 2

CAS: 63132-39-8

Formula: C₅H₁₅NO₇P₂

Color and Shape: White To Off-White Solid

Molecular weight: 263.12

Ref: 4Z-I-109

Olpadronic acid

CAS: 63132-39-8

Olpadronic acid is a pharmacological agent that inhibits the activity of specific enzymes, such as alkaline phosphatase and osteopontin. It has been shown to inhibit prostate cancer cells, by targeting intracellular targets such as cytosolic calcium and bone-specific alkaline phosphatase. Olpadronic acid has also been found to be effective against infectious diseases, including malaria and tuberculosis. It is used in experimental models for the treatment of bone cancer and other diseases. The monosodium salt form of olpadronic acid has been shown to have an effect on dextran sulfate production, which may be related to its ability to inhibit enzymes involved in the synthesis of this molecule.

Formula: C₅H₁₅NO₇P₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 263.12 g/mol

Ref: 3D-FO26559