CAS 6315-89-5

3,4-Dimethoxyaniline

Description:

3,4-Dimethoxyaniline, with the CAS number 6315-89-5, is an organic compound belonging to the class of anilines, which are aromatic amines. It features a benzene ring substituted with two methoxy groups (-OCH₃) at the 3 and 4 positions and an amino group (-NH₂) at the 1 position. This compound is typically a pale yellow to brown solid at room temperature and is known for its moderate solubility in organic solvents such as ethanol and ether, while being less soluble in water. 3,4-Dimethoxyaniline is used in various applications, including as an intermediate in the synthesis of dyes, pigments, and pharmaceuticals. Its chemical structure allows it to participate in electrophilic aromatic substitution reactions, making it a versatile building block in organic synthesis. Additionally, it may exhibit biological activity, which warrants careful handling due to potential toxicity. As with many anilines, it is important to consider safety measures when working with this compound due to its potential health hazards.

Formula: C₈H₁₁NO₂

InChI: InChI=1S/C8H11NO2/c1-10-7-4-3-6(9)5-8(7)11-2/h3-5H,9H2,1-2H3

InChI key: InChIKey=LGDHZCLREKIGKJ-UHFFFAOYSA-N

SMILES: O(C)C1=C(OC)C=C(N)C=C1

Synonyms:

• 2-Methoxy-4-aminoanisole
• 3,4-Bis(methoxy)aniline
• 3,4-Dimethoxyaniline
• 3,4-Dimethoxybenzenamine
• 3,4-Dimethoxyphenylamine
• 4-Amino-1,2-dimethoxybenzene
• 4-Aminoveratrol
• Aniline, 3,4-dimethoxy-
• Benzenamine, 3,4-dimethoxy-
• NSC 21033
• 4-Aminoveratrole

3,4-Dimethoxyaniline

CAS: 6315-89-5

Formula: C₈H₁₁NO₂

Purity: >98.0%(GC)(T)

Color and Shape: Light yellow to Brown powder to crystal

Molecular weight: 153.18

Ref: 3B-D1485

3,4-Dimethoxyaniline, 98+%

CAS: 6315-89-5

3,4-Dimethoxyaniline is commonly used as fine chemicals, used for pharmaceutical intermediates. This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar pro

Formula: C₈H₁₁NO₂

Purity: 98+%

Color and Shape: Cream to brown, Powder

Molecular weight: 153.18

Ref: 02-A13548

3,4-Dimethoxyaniline

CAS: 6315-89-5

Formula: C₈H₁₁NO₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 153.1784

Ref: IN-DA0033IO

3,4-Dimethoxyaniline (4-Aminoveratrole)

CAS: 6315-89-5

Formula: C₈H₁₁NO₂

Molecular weight: 153.18

Ref: 7W-GK9602

3,4-Dimethoxyaniline

CAS: 6315-89-5

3,4-Dimethoxyaniline

Formula: C₈H₁₁NO₂

Purity: 98%

Color and Shape: light purple (hint of brown) powder

Molecular weight: 153.18g/mol

Ref: 54-OR4959

Cabozantinib Impurity 12

CAS: 6315-89-5

Formula: C₈H₁₁NO₂

Molecular weight: 153.18

Ref: 4Z-C-284018

3,4-Dimethoxyaniline

CAS: 6315-89-5

Applications 3,4-Dimethoxyaniline is used as a reagent in the synthesis of 2-aminothiazoles as sphingosine kinase inhibitors. It is also used in the synthesis of pyridine-3-carboxamide-6-yl-ureas which exhibit antimicrobial activity.
References Yule, I.A., et al.: Eur. J. Med. Chem., 86, 31 (2014); Vogt, D., et al.: Bioorg. Med. Chem., 22, 5354 (2014)

Formula: C₈H₁₁NO₂

Color and Shape: Neat

Molecular weight: 153.18

Ref: TR-D470605

3,4-Dimethoxyaniline

CAS: 6315-89-5

3,4-Dimethoxyaniline is a reactive compound that is used as an inhibitor in chemical reactions to prevent unwanted side-reactions. 3,4-Dimethoxyaniline inhibits the enzyme diazonium salt from binding to biological receptors by reacting with it and converting it into a harmless product. 3,4-Dimethoxyaniline has been shown to inhibit epidermal growth factor (EGF) receptor binding in rat liver microsomes. This inhibition can be reversed by adding redox potential. The presence of malonic acid in the reaction solution increases the production of 3,4-dimethoxyaniline. It also has been shown that this compound enhances congestive heart failure and has properties similar to those of malonic acid.

Formula: C₈H₁₁NO₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 153.18 g/mol

Ref: 3D-FD67158

3,4-Dimethoxyaniline

CAS: 6315-89-5

Formula: C₈H₁₁NO₂

Purity: 97%

Color and Shape: Solid, Powder or Crystalline Powder or Solid or Chunks

Molecular weight: 153.181

Ref: 10-F024561

Cabozantinib Impurity 4

CAS: 6315-89-5

Formula: C₈H₁₁NO₂

Molecular weight: 153.18

Ref: ST-EA-CP-C46011