CAS 6320-51-0

5-(4-Methoxybenzylidene)-thiazolidine-2,4-dione

Description:

5-(4-Methoxybenzylidene)-thiazolidine-2,4-dione, also known by its CAS number 6320-51-0, is a synthetic organic compound characterized by its thiazolidine core structure, which features a five-membered ring containing both sulfur and nitrogen atoms. This compound typically exhibits a yellow to orange crystalline appearance and is soluble in organic solvents. The presence of the methoxybenzylidene group contributes to its potential biological activity, making it of interest in medicinal chemistry. Thiazolidinediones, the broader class of compounds to which this substance belongs, are known for their role in pharmacology, particularly in the treatment of diabetes and metabolic disorders, due to their ability to enhance insulin sensitivity. The compound may also exhibit antioxidant and anti-inflammatory properties, although specific biological activities can vary. Its chemical stability, reactivity, and potential applications in drug development make it a subject of ongoing research in various fields, including organic synthesis and pharmacology.

Formula: C₁₁H₉NO₃S

InChI: InChI=1S/C11H9NO3S/c1-15-8-4-2-7(3-5-8)6-9-10(13)12-11(14)16-9/h2-6H,1H3,(H,12,13,14)

InChI key: InChIKey=VRUKGUBMRBLJJW-UHFFFAOYSA-N

SMILES: C(=C1C(=O)NC(=O)S1)C2=CC=C(OC)C=C2

Synonyms:

• 2,4-Thiazolidinedione, 5-[(4-methoxyphenyl)methylene]-
• 5-[(4-Methoxyphenyl)methylidene]thiazolidine-2,4-dione
• 5-[(4-Methoxyphenyl)methylene]-2,4-thiazolidinedione
• 5-(4-Methoxybenzylidene)-2,4-dioxotetrahydro-1,3-thiazole
• 2,4-Thiazolidinedione, 5-(p-methoxybenzylidene)-

2,4-Thiazolidinedione, 5-p-methoxybenzylidene-

CAS: 6320-51-0

Formula: C₁₁H₉NO₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 235.2591

Ref: IN-DA00ELXE

Pim-1/2 kinase inhibitor 1

CAS: 6320-51-0

Pim-1/2 kinase inhibitor 1

Purity: ≥98%

Molecular weight: 235.26g/mol

Ref: 54-BUP11612

Pim-1/2 kinase inhibitor 1

CAS: 6320-51-0

Orally active Pim-1/2 inhibitor blocks kinase phosphorylation; used in prostate cancer research.

Formula: C₁₁H₉NO₃S

Purity: 99.78%

Color and Shape: Solid

Molecular weight: 235.26

Ref: TM-T9229

5-(4-Methoxybenzylidene)thiazolidine-2,4-dione

CAS: 6320-51-0

Purity: 98%

Molecular weight: 235.2599945

Ref: 10-F870205

5-(4-Methoxy-benzylidene)-thiazolidine-2,4-dione

CAS: 6320-51-0

5-(4-Methoxy-benzylidene)-thiazolidine-2,4-dione is a drug that binds to the transcription factor NF-κB and prevents its translocation into the nucleus. It is used in the treatment of inflammatory diseases such as rheumatoid arthritis, psoriasis, and Crohn's disease. 5-(4-Methoxy-benzylidene)-thiazolidine-2,4-dione also has hepatoprotective effects by inhibiting oxidative stress and proinflammatory cytokines. This drug can be administered orally or intravenously.

Formula: C₁₁H₉NO₃S

Purity: Min. 95%

Molecular weight: 235.26 g/mol

Ref: 3D-GAA32051