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CAS 63208-82-2

:

Pifithrin

Description:
Pifithrin, with the CAS number 63208-82-2, is a chemical compound primarily known for its role as a p53 inhibitor. It is often studied in the context of cancer research, particularly for its ability to modulate the activity of the p53 protein, which is a crucial tumor suppressor involved in regulating the cell cycle and preventing tumor formation. Pifithrin has been shown to interfere with p53-mediated transcriptional activation, thereby influencing cellular responses to stress and apoptosis. The compound is typically characterized by its small molecular size and specific structural features that allow it to interact with the p53 pathway. In laboratory settings, Pifithrin is utilized to explore the mechanisms of p53 function and its implications in cancer biology, as well as to investigate potential therapeutic strategies that could arise from manipulating p53 activity. However, as with any chemical substance, safety and handling precautions are essential when working with Pifithrin in research environments.
Formula:C16H18N2OS·BrH
InChI:InChI=1S/C16H18N2OS.BrH/c1-11-6-8-12(9-7-11)14(19)10-18-13-4-2-3-5-15(13)20-16(18)17;/h6-9,17H,2-5,10H2,1H3;1H
InChI key:InChIKey=HAGVCKULCLQGRF-UHFFFAOYSA-N
SMILES:C(C(=O)C1=CC=C(C)C=C1)N2C3=C(SC2=N)CCCC3.Br
Synonyms:
  • Pifithrin
  • Ethanone, 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-, hydrobromide (1:1)
  • Pifithrin-α
  • Ethanone, 1-(4-methylphenyl)-2-(4,5,6,7-tetrahydro-2-imino-3(2H)-benzothiazolyl)-, monohydrobromide
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