CAS 6322-56-1

4-Hydroxy-3-nitroacetophenone

Description:

4-Hydroxy-3-nitroacetophenone, with the CAS number 6322-56-1, is an organic compound characterized by its aromatic structure, which includes a hydroxyl group (-OH) and a nitro group (-NO2) attached to an acetophenone framework. This compound typically appears as a yellow to orange crystalline solid and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. It exhibits both acidic and basic properties due to the presence of the hydroxyl group, which can participate in hydrogen bonding. The nitro group contributes to its reactivity, making it a useful intermediate in organic synthesis, particularly in the preparation of dyes and pharmaceuticals. Additionally, 4-Hydroxy-3-nitroacetophenone can undergo various chemical reactions, including nitration, reduction, and acylation, which are valuable in synthetic organic chemistry. Safety precautions should be taken when handling this compound, as it may pose health risks if ingested or inhaled.

Formula: C₈H₇NO₄

InChI: InChI=1S/C8H7NO4/c1-5(10)6-2-3-8(11)7(4-6)9(12)13/h2-4,11H,1H3

InChI key: InChIKey=MMNKVWGVSHRIJL-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=CC(C(C)=O)=CC=C1O

Synonyms:

• (4-Hydroxy-3-nitrophenyl)ethan-1-one
• 1-(4-Hydroxy-3-nitrophenyl)ethan-1-one
• 1-(4-Hydroxy-3-nitrophenyl)ethanone
• 2-Nitro-4-acetylphenol
• 3-Nitro-4-Hydroxyacttophenone
• 3′-Nitro-4′-hydroxyacetophenone
• 4-Acetyl-2-Nitrophenolate
• 4-Acetyl-2-nitrophenol
• Acetophenone, 4′-hydroxy-3′-nitro-
• Ethanone, 1-(4-hydroxy-3-nitrophenyl)-
• NSC 32113

Ethanone, 1-(4-hydroxy-3-nitrophenyl)-

CAS: 6322-56-1

Formula: C₈H₇NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 181.1455

Ref: IN-DA00IB68

4''-Hydroxy-3''-nitroacetophenone

CAS: 6322-56-1

Formula: C₈H₇NO₄

Molecular weight: 181.15

Ref: 7W-GK7599

4'-Hydroxy-3'-nitroacetophenone

CAS: 6322-56-1

Formula: C₈H₇NO₄

Purity: >98.0%(GC)

Color and Shape: Light orange to Yellow to Green powder to crystal

Molecular weight: 181.15

Ref: 3B-H0968

4'-Hydroxy-3'-nitroacetophenone

CAS: 6322-56-1

4'-Hydroxy-3'-nitroacetophenone

Formula: C₈H₇NO₄

Purity: 98%

Color and Shape: solid

Molecular weight: 181.15g/mol

Ref: 54-OR4297

4-Hydroxy-3-Nitroacetophenone

CAS: 6322-56-1

Formula: C₈H₇NO₄

Molecular weight: 181.15

Ref: 4Z-A-128010

4'-Hydroxy-3'-nitroacetophenone

CAS: 6322-56-1

4'-Hydroxy-3'-nitroacetophenone is a synthetic compound that has been used as an xanthine oxidase inhibitor. It has been shown to reversibly inhibit xanthine oxidase and prevent the accumulation of toxic metabolites that are produced by this enzyme. 4'-Hydroxy-3'-nitroacetophenone also inhibits the activities of other enzymes, such as covalent adducts with protein molecules and transfer reactions. The molecular modeling study of this compound showed that it binds to the active site of xanthine oxidase, forming a covalent adduct between the reactive oxygen species (ROS) and the phenolic OH group on the inhibitor molecule. 4'-Hydroxy-3'-nitroacetophenone was found to be safe in clinical studies, with reversible covalent binding and no inhibition of protein synthesis or cell growth at therapeutic concentrations.

Formula: C₈H₇NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 181.15 g/mol

Ref: 3D-FH24225

4-Acetyl-2-nitro-phenol

CAS: 6322-56-1

Formula: C₈H₇NO₄

Purity: 98%

Color and Shape: Pale yellow to yellow green powder

Molecular weight: 181.147

Ref: 10-F040355

4-Hydroxy-3-Nitroacetophenone

CAS: 6322-56-1

Formula: C₈H₇NO₄

Molecular weight: 181.15

Ref: ST-EA-CP-A265005