CAS 63284-72-0: Citalopram N-oxide

Description: Citalopram N-oxide is a chemical compound that is a derivative of the selective serotonin reuptake inhibitor (SSRI) citalopram, which is primarily used in the treatment of depression and anxiety disorders. The N-oxide form indicates that it has undergone oxidation, specifically at the nitrogen atom in the piperidine ring of the citalopram structure. This modification can influence its pharmacological properties, potentially affecting its efficacy and metabolism. Citalopram N-oxide is characterized by its molecular formula, which reflects the presence of carbon, hydrogen, nitrogen, and oxygen atoms. It is typically a white to off-white solid and is soluble in organic solvents. The compound's pharmacokinetics, including its absorption, distribution, metabolism, and excretion, may differ from those of citalopram, which could have implications for its therapeutic use. As with any pharmaceutical compound, safety and toxicity profiles are essential considerations, and further research may be necessary to fully understand its biological activity and potential applications in clinical settings.

Formula: C₂₀H₂₁FN₂O₂

InChI: InChI=1S/C20H21FN2O2/c1-23(2,24)11-3-10-20(17-5-7-18(21)8-6-17)19-9-4-15(13-22)12-16(19)14-25-20/h4-9,12H,3,10-11,14H2,1-2H3

InChI key: InChIKey=DIOGFDCEWUUSBQ-UHFFFAOYSA-N

SMILES: N#CC1=CC=C2C(=C1)COC2(C3=CC=C(F)C=C3)CCCN(=O)(C)C

Synonyms:

• 5-Isobenzofurancarbonitrile, 1-[3-(dimethyloxidoamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-
• Lu 11-305
• Citalopram N-oxide
• 1-[3-(Dimethyloxidoamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-5-isobenzofurancarbonitrile
• 5-Isobenzofurancarbonitrile, 1-[3-(dimethylamino)propyl]-1-(4-fluorophenyl)-1,3-dihydro-, N1-oxide

Citalopram N-Oxide

CAS: 63284-72-0

• Formula: C₂₀H₂₁FN₂O₂
• Color and Shape: Neat
• Molecular weight: 340.39

Citalopram N-Oxide

CAS: 63284-72-0

Impurity Escitalopram EP Impurity H; Citalopram USP Related Compound E Applications Citalopram N-Oxide (Escitalopram EP …

• Formula: C₂₀H₂₁FN₂O₂
• Color and Shape: Neat
• Molecular weight: 340.39

Citalopram N-oxide

CAS: 63284-72-0

Serotonin uptake inhibitor; anti-depressant

• Formula: C₂₀H₂₁FN₂O₂
• Purity: Min. 95%
• Color and Shape: Solid
• Molecular weight: 340.39 g/mol