CAS 63357-45-9

2-(N-acetylacetamido)-3-(4-hydroxy-3-methoxyphenyl)propanoic acid

Description:

2-(N-acetylacetamido)-3-(4-hydroxy-3-methoxyphenyl)propanoic acid, with the CAS number 63357-45-9, is a chemical compound characterized by its complex structure that includes an acetylacetamido group and a phenolic moiety. This compound typically exhibits properties associated with both amides and carboxylic acids, including potential solubility in polar solvents due to the presence of hydroxyl and carboxyl functional groups. The methoxy group contributes to its aromatic characteristics, potentially influencing its reactivity and interactions in biological systems. The presence of the hydroxy group may enhance its ability to form hydrogen bonds, affecting its solubility and stability. This compound may also exhibit biological activity, making it of interest in pharmaceutical research. Its specific applications and behavior in various chemical environments would depend on further studies, including its reactivity, stability under different conditions, and potential therapeutic effects. Overall, this compound represents a unique combination of functional groups that could lead to diverse applications in medicinal chemistry and related fields.

2-acetamido-3-(4-hydroxy-3-methoxyphenyl)propanoic acid

CAS: 63357-45-9

Formula: C₁₂H₁₅NO₅

Purity: 95%

Color and Shape: Solid

Molecular weight: 253.2512

Ref: IN-DA01BXVU

N-Acetyl-3-methoxytyrosine

Controlled Product

CAS: 63357-45-9

Applications N-Acetyl-3-methoxytyrosine is an intermediate in the synthesis of rac 3-O-Methyl DOPA (Levodopa EP Impurity C) (M303805), which is an impurity of Levodopa (D533751). A useful marker that can be used to screen for the absense of Aromatic L-amino acid decarboxylase (AADC).
References Tabar, et al.: Pharmacol. Biochem. Behav., 33, 139 (1989), De Souza Silva, et al.: J. Neurochem., 68, 233 (1997), Feigin, A., et al.: Neurology, 57, 2083 (2001), Perera, A., et al.: J. Labelled Comp. Radiopharm., 46, 389 (2003),

Formula: C₁₂H₁₅NO₅

Color and Shape: Neat

Molecular weight: 253.251

Ref: TR-A459635

2-Acetamido-3-(4-hydroxy-3-methoxyphenyl)propanoic acid

CAS: 63357-45-9

2-Acetamido-3-(4-hydroxy-3-methoxyphenyl)propanoic acid is an organic acid that is used as a diagnostic agent for dopamine. It has been shown to be effective in the diagnosis of pediatric cases of DOPA responsive dystonia and DOPA responsive choreoathetosis. This compound may be used to diagnose Parkinson's disease, although it is not yet approved for this use. 2-Acetamido-3-(4-hydroxy-3-methoxyphenyl)propanoic acid is also used as a biochemical marker in the retrospective diagnosis of monoamine oxidase inhibitor therapy and in the clinical development of drugs with monoamine oxidase inhibiting activity.

Formula: C₁₂H₁₅NO₅

Purity: Min. 95%

Molecular weight: 253.25 g/mol

Ref: 3D-NCA35745