CAS 6336-50-1

6-Benzyl-2-thiouracil

Description:

6-Benzyl-2-thiouracil is an organic compound that belongs to the class of thiouracils, which are derivatives of uracil where sulfur replaces the oxygen atom at the 2-position. This compound is characterized by the presence of a benzyl group at the 6-position of the uracil ring, which contributes to its unique chemical properties. It typically appears as a white to off-white solid and is soluble in organic solvents. The compound exhibits biological activity, particularly in the field of medicinal chemistry, where it has been studied for its potential use as an antithyroid agent due to its ability to inhibit thyroid hormone synthesis. Additionally, 6-benzyl-2-thiouracil may also exhibit antioxidant properties and has been investigated for its effects on various biological pathways. Its molecular structure allows for interactions with various biological targets, making it a subject of interest in pharmacological research. As with many thiouracil derivatives, it is important to handle this compound with care, considering its potential biological effects and toxicity.

Formula: C₁₁H₁₀N₂OS

InChI: InChI=1S/C11H10N2OS/c14-10-7-9(12-11(15)13-10)6-8-4-2-1-3-5-8/h1-5,7H,6H2,(H2,12,13,14,15)

InChI key: InChIKey=PNXBXCRWXNESOV-UHFFFAOYSA-N

SMILES: C(C1=CC(=O)NC(=S)N1)C2=CC=CC=C2

Synonyms:

• 2,3-Dihydro-6-(phenylmethyl)-2-thioxo-4(1H)-pyrimidinone
• 4(1H)-Pyrimidinone, 2,3-dihydro-6-(phenylmethyl)-2-thioxo-
• 6-Benzyl-2-thiouracil
• 6-Benzyl-4-hydroxy-2-mercaptopyrimidine
• 6-benzyl-2-thioxo-2,3-dihydropyrimidin-4(1H)-one
• Basdene
• Bentiuracil
• Betiuracil
• NSC 39511
• NSC 6508
• Uracil, 6-benzyl-2-thio-

6-Benzyl-2-mercaptopyrimidin-4(3h)-one

CAS: 6336-50-1

Formula: C₁₁H₁₀N₂OS

Purity: 98%

Color and Shape: Solid

Molecular weight: 218.2749

Ref: IN-DA00EG07

Benzylthiouracil

CAS: 6336-50-1

Benzylthiouracil

Purity: 98%

Molecular weight: 218.28g/mol

Ref: 54-OR1032037

6-Benzyl-2-thiouracil

Controlled Product

CAS: 6336-50-1

Applications 6-Benzyl-2-thiouracil (cas# 6336-50-1) is a useful research chemical.

Formula: C₁₁H₁₀N₂OS

Color and Shape: Off-White

Molecular weight: 218.27

Ref: TR-B315158

Benzylthiouracil

CAS: 6336-50-1

Benzylthiouracil (6-Benzyl-2-thiouracil) induces ANCA-associated glomerulonephritis in Graves' disease patients and is used to study hyperthyroidism.

Formula: C₁₁H₁₀N₂OS

Purity: 99.65%

Color and Shape: Solid

Molecular weight: 218.28

Ref: TM-T60268

6-Benzyl-2-thiouracil

CAS: 6336-50-1

6-Benzyl-2-thiouracil (BTS) is a benzyl group with the chemical formula C12H8N2OS. It has been used as an anti-infective agent and has been shown to have a clinical relevance in treating hepatitis, cutaneous lesions, and inflammatory bowel disease. BTS is metabolized through oxidation of the benzyl group by cytochrome P450 enzymes. This active form has been shown to inhibit mitochondrial fatty acid synthesis, which may be a pathogenic mechanism for BTS in women with metabolic syndrome. The metabolism of BTS also results in its conversion to 2-benzylpyrimidine, which can be converted into a carcinogen by N-nitrosation.

Formula: C₁₁H₁₀N₂OS

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 218.28 g/mol

Ref: 3D-NB67066

Benzylthiouracil

CAS: 6336-50-1

Purity: 98%

Molecular weight: 218.27

Ref: 10-F603965