CAS 63388-37-4

Declenperone

Description:

Declenperone, with the CAS number 63388-37-4, is a chemical compound classified as an atypical antipsychotic. It is primarily known for its use in the treatment of schizophrenia and other psychiatric disorders. The substance exhibits a unique pharmacological profile, acting as a dopamine antagonist, which helps in modulating neurotransmitter activity in the brain. Declenperone is characterized by its ability to reduce psychotic symptoms while minimizing extrapyramidal side effects commonly associated with traditional antipsychotics. Its chemical structure includes a piperazine moiety, contributing to its binding affinity for various neurotransmitter receptors, including serotonin and dopamine receptors. The compound is typically administered in oral form and has a specific dosage regimen to optimize therapeutic effects while reducing potential side effects. As with many psychotropic medications, monitoring for adverse reactions is essential during treatment. Overall, Declenperone represents a significant advancement in the pharmacotherapy of mental health disorders, offering an alternative for patients who may not respond well to conventional treatments.

Formula: C₂₂H₂₄FN₃O₂

InChI: InChI=1/C22H24FN3O2/c23-18-8-6-16(7-9-18)21(27)17-10-14-25(15-11-17)12-3-13-26-20-5-2-1-4-19(20)24-22(26)28/h1-2,4-9,17H,3,10-15H2,(H,24,28)

SMILES: c1ccc2c(c1)nc(n2CCCN1CCC(CC1)C(=O)c1ccc(cc1)F)O

Synonyms:

• Declenperone [USAN:INN]
• 1-(3-(4-(4-Fluorbenzoyl)piperidino)propyl)-2,3-dihydro-2-benzimidazolon
• 1-(3-(4-(p-Fluorobenzoyl)piperidino)propyl)-2-benzimidazolinone
• 2H-Benzimidazol-2-one, 1-(3-(4-(4-fluorobenzoyl)-1-piperidinyl)propyl)-1,3-dihydro-
• Declenperona
• Declenperona [INN-Spanish]
• Declenperonum
• Declenperonum [INN-Latin]
• R 33,204
• Unii-280Vgv0X4H
• 1-{3-[4-(4-fluorobenzoyl)piperidin-1-yl]propyl}-1,3-dihydro-2H-benzimidazol-2-one

Declenperon

Controlled Product

CAS: 63388-37-4

Formula: C₂₂H₂₄FN₃O₂

Color and Shape: Neat

Molecular weight: 381.443

Ref: TR-D226820

Declenperon-d6

Controlled Product

CAS: 63388-37-4

Formula: C₂₂D₆H₁₈FN₃O₂

Color and Shape: Neat

Molecular weight: 387.48

Ref: TR-D226822

Declenperone

CAS: 63388-37-4

Declenperon is a reagent for antimalarial lead identification and aids in creating serotonin S2 antagonists.

Formula: C₂₂H₂₄FN₃O₂

Color and Shape: Solid

Molecular weight: 381.44

Ref: TM-T68962