
CAS 634207-55-9
:Adenosine, 8-chloro-2′-O-methyl-
Description:
Adenosine, 8-chloro-2′-O-methyl- is a modified nucleoside that features a chlorine atom at the 8-position of the adenine base and a methoxy group at the 2′ position of the ribose sugar. This compound is characterized by its structural modifications that enhance its biological activity and stability compared to unmodified adenosine. The presence of the chlorine atom can influence its interaction with adenosine receptors, potentially altering its pharmacological properties. The 2′-O-methyl modification typically increases resistance to enzymatic degradation, making it more stable in biological systems. This compound is of interest in biochemical research and drug development, particularly in studies related to cellular signaling and therapeutic applications. Its CAS number, 634207-55-9, uniquely identifies it in chemical databases, facilitating its study and application in various scientific fields. Overall, adenosine, 8-chloro-2′-O-methyl- represents a significant modification of the natural nucleoside, with potential implications in pharmacology and molecular biology.
Formula:C11H14ClN5O4
InChI:InChI=1S/C11H14ClN5O4/c1-20-7-6(19)4(2-18)21-10(7)17-9-5(16-11(17)12)8(13)14-3-15-9/h3-4,6-7,10,18-19H,2H2,1H3,(H2,13,14,15)/t4-,6-,7-,10-/m1/s1
InChI key:InChIKey=IXTQMSFHXDXWKT-KQYNXXCUSA-N
SMILES:ClC=1N(C=2C(N1)=C(N)N=CN2)[C@H]3[C@H](OC)[C@H](O)[C@@H](CO)O3
Synonyms:- Adenosine, 8-chloro-2′-O-methyl-
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8-Chloro-2'-O-methyl adenosine
CAS:<p>Nucleoside Derivatives - Halo-nucleosides, 8-Modified purine nucleosides, 2’-modified nucleosides</p>Formula:C11H14ClN5O4Color and Shape:SolidMolecular weight:315.71
