CAS 634911-80-1

3-[[(tert-Butoxy)carbonyl]amino]-5-fluoro-4-oxopentanoic acid methyl ester

Description:

3-[[(tert-Butoxy)carbonyl]amino]-5-fluoro-4-oxopentanoic acid methyl ester, with the CAS number 634911-80-1, is a synthetic organic compound characterized by its complex structure that includes a fluorinated moiety, a carbonyl group, and an ester functional group. This compound features a tert-butoxycarbonyl (Boc) protecting group, which is commonly used in peptide synthesis to protect amine functionalities. The presence of a fluorine atom enhances its biological activity and lipophilicity, potentially influencing its pharmacokinetic properties. The methyl ester group contributes to its solubility and reactivity, making it suitable for various chemical transformations. Typically, compounds of this nature are explored in medicinal chemistry for their potential applications in drug development, particularly in the design of enzyme inhibitors or other therapeutic agents. Its stability, reactivity, and functional groups make it a valuable intermediate in organic synthesis and pharmaceutical research. As with many synthetic compounds, handling should be done with care, following appropriate safety protocols.

Formula: C₁₁H₁₈FNO₅

Synonyms:

• 3-[[(tert-Butoxy)carbonyl]amino]-5-fluoro-4-oxopentanoic acid methyl ester
• Caspase3-Inhibitor Boc-D-FMK
• BOC-D-FMK
• Pentanoic acid, 3-[[(1,1-diMethylethoxy)carbonyl]aMino]-5-fluoro-4-oxo-, Methyl ester
• Caspase Inhibitor Boc-D-FMK
• 1-dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-
• (Pentanoic acid, 3-[[(1,1-dimethylethoxy)carbonyl]amino]-5-fluoro-4-oxo-, methyl ester)

BOC-D-FMK

CAS: 634911-80-1

BOC-D-FMK

Molecular weight: 263.26g/mol

Ref: 54-BUP02410

BOC-D-FMK

CAS: 634911-80-1

Boc-D-FMK is an irreversible, cell-permeable, and broad-spectrum caspase inhibitor and inhibits apoptosis stimulated by TNF-α (IC50: 39 μM).

Formula: C₁₁H₁₈FNO₅

Purity: 97.02%

Color and Shape: Solid

Molecular weight: 263.26

Ref: TM-T10580

Caspase inhibitor III

CAS: 634911-80-1

Caspase inhibitor III is a potent caspase-3 and -7 inhibitor with IC50 values of 0.8 μM and 2.6 μM, respectively. It also inhibits the activation of other caspases including caspase-9, -6, and -2. Caspase inhibitor III binds to the active site of caspase-3 (the catalytic domain) by a noncompetitive inhibition mechanism that does not require ATP binding or hydrolysis.

Formula: C₁₁H₁₈FNO₅

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 263.26 g/mol

Ref: 3D-BL181115