CAS 634911-81-2

N-[(benzyloxy)carbonyl]-L-valyl-N-[3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide

Description:

N-[(benzyloxy)carbonyl]-L-valyl-N-[3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide, with CAS number 634911-81-2, is a synthetic compound that belongs to the class of peptide derivatives. This substance features a complex structure characterized by the presence of amino acid residues, specifically L-valine and L-alanine, which are linked through peptide bonds. The compound also contains a benzyloxycarbonyl (Z) protecting group, which is commonly used in peptide synthesis to protect the amino group of the amino acid. Additionally, it incorporates a fluorinated moiety, which can enhance biological activity or alter pharmacokinetic properties. The methoxy and keto groups contribute to its overall reactivity and potential interactions in biological systems. Such compounds are often investigated for their potential therapeutic applications, particularly in the fields of medicinal chemistry and drug development, due to their ability to mimic natural peptides and proteins. As with many synthetic compounds, its stability, solubility, and biological activity would be of interest in research and application contexts.

Formula: C₂₂H₃₀FN₃O₇

InChI: InChI=1/C22H30FN3O7/c1-13(2)19(26-22(31)33-12-15-8-6-5-7-9-15)21(30)24-14(3)20(29)25-16(17(27)11-23)10-18(28)32-4/h5-9,13-14,16,19H,10-12H2,1-4H3,(H,24,30)(H,25,29)(H,26,31)/t14-,16?,19-/m0/s1

SMILES: CC(C)[C@@H](C(=N[C@@H](C)C(=NC(CC(=O)OC)C(=O)CF)O)O)N=C(O)OCc1ccccc1

Synonyms:

• N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamideSee Z359870
• Z-VAD(OH)-FMK
• methyl 5-fluoro-3-[[(2S)-2-[[(2S)-3-methyl-2-(phenylmethoxycarbonylamino)butanoyl]amino]propanoyl]amino]-4-oxopentanoate
• L-Alaninamide, N-[(phenylmethoxy)carbonyl]-L-valyl-N-[3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]- (9CI)
• N-[(Benzyloxy)carbonyl]-L-valyl-N-(5-fluoro-1-methoxy-1,4-dioxo-3 -pentanyl)-L-alaninamide
• N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide

Z-Val-Ala-DL-Asp(OMe)-fluoromethylketone

CAS: 634911-81-2

Z-VAD(OMe)-FMK, a pan-caspase inhibitor, is a competitive irreversible peptide inhibitor and blocks caspase-1 family and caspase-3 family enzymes. The methyl ester of Z-VAD-FMK has been used in studies to support the hypothesis that inhibitors of caspases can limit brain infarction resulting from the permanent obstruction of a brain artery.

Formula: C₂₂H₃₀FN₃O₇

Purity: 96.3%

Color and Shape: White Powder

Molecular weight: 467.5

Ref: 01-4027403

(Iso)-Z-VAD(OMe)-FMK

CAS: 634911-81-2

(Iso)-Z-VAD(OMe)-FMK is an isomer of Z-VAD(OMe)-FMK, which is a pan-caspase inhibitor with irreversible properties. Z-VAD(OMe)-FMK is also an inhibitor UCHL1.

Formula: C₂₂H₃₀FN₃O₇

Purity: 97.10%

Color and Shape: Soild

Molecular weight: 467.49

Ref: TM-T88862

(Iso)-Z-VAD(OMe)-FMK

CAS: 634911-81-2

(Iso)-Z-VAD(OMe)-FMK

Purity: ≥95%

Molecular weight: 467.49g/mol

Ref: 54-BUP18634

Z-VAD(OMe)-FMK

CAS: 634911-81-2

Z-VAD(OMe)-FMK

Molecular weight: 467.49g/mol

Ref: 54-BIBA1009

N-[(Phenylmethoxy)carbonyl]-L-valyl-N-[3-fluoro-1-(2-methoxy-2-oxoethyl)-2-oxopropyl]-L-alaninamide

Controlled Product

CAS: 634911-81-2

Formula: C₂₁H₂₈FN₃O₇

Color and Shape: Neat

Molecular weight: 453.461

Ref: TR-P335745