CAS 635-65-4

Bilirubin

Description:

Bilirubin is a yellowish compound that is a product of the breakdown of heme, a component of hemoglobin found in red blood cells. It is primarily produced in the liver and is excreted in bile, playing a crucial role in the body's waste management system. Bilirubin exists in two main forms: unconjugated (indirect) bilirubin, which is lipid-soluble and not water-soluble, and conjugated (direct) bilirubin, which is water-soluble due to its conjugation with glucuronic acid. This transformation facilitates its excretion from the body. Elevated levels of bilirubin can lead to jaundice, a condition characterized by yellowing of the skin and eyes, indicating potential liver dysfunction or hemolysis. Bilirubin's chemical structure includes a series of conjugated double bonds, contributing to its characteristic color. It also has antioxidant properties, which may play a role in protecting cells from oxidative stress. The CAS number 635-65-4 specifically identifies the unconjugated form of bilirubin, which is important in clinical diagnostics and understanding various health conditions.

Formula: C₃₃H₃₆N₄O₆

InChI: InChI=1S/C33H36N4O6/c1-7-20-19(6)32(42)37-27(20)14-25-18(5)23(10-12-31(40)41)29(35-25)15-28-22(9-11-30(38)39)17(4)24(34-28)13-26-16(3)21(8-2)33(43)36-26/h7-8,13-14,34-35H,1-2,9-12,15H2,3-6H3,(H,36,43)(H,37,42)(H,38,39)(H,40,41)/b26-13-,27-14-

InChI key: InChIKey=BPYKTIZUTYGOLE-IFADSCNNSA-N

SMILES: C(C1=C(CCC(O)=O)C(C)=C(/C=C\2/C(C=C)=C(C)C(=O)N2)N1)C3=C(CCC(O)=O)C(C)=C(/C=C\4/C(C)=C(C=C)C(=O)N4)N3

Synonyms:

• (4Z,15Z)-Bilirubin IXα
• (Z,Z)-Bilirubin
• (Z,Z)-Bilirubin IXα
• 2,17-Diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-21H-biline-8,12-dipropanoic Acid
• 21H-Biline-8,12-dipropanoic acid, 2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-
• 3-[2-[[3-(2-carboxyethyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl]methyl]-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoic acid
• 3-[2-[[3-(2-carboxyethyl)-4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-2-yl]methyl]-4-methyl-5-[(Z)-(3-methyl-5-oxo-4-vinyl-pyrrol-2-ylidene)methyl]-2H-pyrrol-3-yl]propanoic acid
• 3-[4-methyl-2-[[4-methyl-5-[(Z)-(4-methyl-5-oxo-3-vinyl-pyrrol-2-ylidene)methyl]-3-(3-oxido-3-oxo-propyl)-1H-pyrrol-2-yl]methyl]-5-[(Z)-(3-methyl-5-oxo-4-vinyl-pyrrol-2-ylidene)methyl]-1H-pyrrol-3-yl]propanoate
• Biline-8,12-dipropionic acid, 1,10,19,22,23,24-hexahydro-2,7,13,17-tetramethyl-1,19-dioxo-3,18-divinyl-
• Bilirubin IXα
• Bilirubin Powder
• Bilirubina
• Bilirubine
• Biliyubin
• Cholerythrin
• Hematoidin
• Nsc 26685

Bilirubin

CAS: 635-65-4

Formula: C₃₃H₃₆N₄O₆

Purity: >80.0%(HPLC)

Color and Shape: Orange to Brown powder to crystal

Molecular weight: 584.67

Ref: 3B-B0460

21H-Biline-8,12-dipropanoic acid,2,17-diethenyl-1,10,19,22,23,24-hexahydro-3,7,13,18-tetramethyl-1,19-dioxo-

CAS: 635-65-4

Formula: C₃₃H₃₆N₄O₆

Purity: 97%

Color and Shape: Solid

Molecular weight: 584.6621

Ref: IN-DA00IB88

Bilirubin

CAS: 635-65-4

Formula: C₃₃H₃₆N₄O₆

Purity: ≥ 95%

Color and Shape: Orange to brown powder

Molecular weight: 584.68

Ref: 7W-GE4042

Bilirubin

CAS: 635-65-4

Bilirubin

Purity: ≥98%

Molecular weight: 584.66g/mol

Ref: 54-BUP16015

Bilirubin

CAS: 635-65-4

Bilirubin

Formula: C₃₃H₃₆N₄O₆

Purity: 97% (nmr) (Typical Value in Batch COA)

Color and Shape: orange solid

Molecular weight: 584.66g/mol

Ref: 54-BIB0134

Bilirubin

CAS: 635-65-4

Formula: C₃₃H₃₆N₄O₆

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 584.673

Ref: BP-BP3455

Bilirubin

CAS: 635-65-4

Formula: C₃₃H₃₆N₄O₆

Purity: >95%

Color and Shape: Solid

Molecular weight: 584.67

Ref: FT-B584-9

Bilirubin

CAS: 635-65-4

Formula: C₃₃H₃₆N₄O₆

Molecular weight: 584.67

Ref: 4Z-B-275001

Bilirubin

CAS: 635-65-4

Bilirubin (Principal bile pigment) is a metabolite of hemoglobin in the blood. Bilirubin has antimutagenic and antioxidant effects. Cost-effective and quality-assured.

Formula: C₃₃H₃₆N₄O₆

Purity: 99.1% - 99.59%

Color and Shape: Solid

Molecular weight: 584.66

Ref: TM-T2934

Bilirubin (>90%)

Controlled Product

CAS: 635-65-4

Applications Principal pigment of bile and constituent of many biliary calculi.
References Stenhagen, R., et al.: Biochem. J., 33, 1591 (1939), Gray, et al.: J. Chem. Soc., 2264, 2268 (1961),

Formula: C₃₃H₃₆N₄O₆

Purity: >90%

Color and Shape: Neat

Molecular weight: 584.662

Ref: TR-B385300

Bilirubin-d4 (Major) (Technical Grade)

Controlled Product

CAS: 635-65-4

Applications Labelled Bilirubin (B385300), a principal pigment of bile and constituent of many biliary calculi.
References Stenhagen, R., et al.: Biochem. J., 33, 1591 (1939), Gray, et al.: J. Chem. Soc., 2264, 2268 (1961),

Formula: C₃₃H₃₂D₄N₄O₆

Color and Shape: Neat

Molecular weight: 588.69

Ref: TR-B385302

Bilirubin

CAS: 635-65-4

Bilirubin is a product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin. Insoluble yellow coloured bilirubin can be turned into water soluble iso-bilirubin by blue-light irradiation. This is the molecular basis of the standard treatment of neonatal hyperbilirubinemia (or Jaundice) by a fairly simple phototherapy. In a 2018 study by Lee et al., the solubility switch of bilirubin was used in a new type of bilirubin-based carriers for anti-cancer drugs.

Formula: C₃₃H₃₆N₄O₆

Purity: (Uv) Min. 95.0%

Molecular weight: 584.68 g/mol

Ref: 3D-B-2501

Bilirubin - unconjugated

CAS: 635-65-4

Bilirubin is a is a product of heme degradation, produced by the reduction of biliverdin and transported to the liver as a complex with serum albumin. The two main types of bilirubin are conjugated and unconjugated, which differ in their solubility and how they are measured: Conjugated bilirubin (also known as direct bilirubin), this is the water-soluble form of bilirubin which has been conjugated with glucoronic acid and is excreted in the bile.Unconjugated bilirubin (also known as indirect bilirubin), this is the water-insoluble form of bilirubin that is bound to albumin in the blood on the way to the liver. It can't normally be measured directly in blood testing, so it's calculated by subtracting the conjugated bilirubin value from the total bilirubin value.This product, FB01720, contains the unconjugated (water insoluble) form of bilirubin only.

Formula: C₃₃H₃₆N₄O₆

Molecular weight: 584.66 g/mol

Ref: 3D-FB01720

Bilirubin

CAS: 635-65-4

Bilirubin is a product of heme degradation, it is produced in the reticuloendothelial system by the reduction of biliverdin and transported to the liver as a complex with serum albumin. Insoluble yellow coloured bilirubin can be turned into water soluble iso-bilirubin by blue-light irradiation. This is the molecular basis of the standard treatment of neonatal hyperbilirubinemia (or Jaundice) by a fairly simple phototherapy. In a 2018 study by Lee et al., the solubility switch of bilirubin was used in a new type of bilirubin-based carriers for anti-cancer drugs.

Formula: C₃₃H₃₆N₄O₆

Purity: (Uv) Min. 99%

Color and Shape: Powder

Molecular weight: 584.66 g/mol

Ref: 3D-FB01719

Bilirubin extrapure AR, 99%

CAS: 635-65-4

Formula: C₃₃H₃₆N₄O₆

Purity: min. 99%

Color and Shape: Yellowish orange, Crystalline powder

Molecular weight: 584.68

Ref: SR-64839