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CAS 635305-24-7

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5-Chlorothiophene-2-boronic acid pinacol ester

Description:
5-Chlorothiophene-2-boronic acid pinacol ester is an organoboron compound characterized by the presence of a thiophene ring substituted with a chlorine atom and a boronic acid moiety. This compound typically exhibits a pale yellow to light brown appearance and is soluble in organic solvents such as dichloromethane and tetrahydrofuran. The pinacol ester functionality enhances its stability and reactivity, making it useful in various synthetic applications, particularly in cross-coupling reactions like Suzuki-Miyaura coupling, which is pivotal in the formation of carbon-carbon bonds. The presence of the boronic acid group allows for the formation of stable complexes with diols and other Lewis bases, facilitating its use in organic synthesis. Additionally, the chlorine substituent can serve as a leaving group in nucleophilic substitution reactions, further expanding its utility in chemical transformations. Overall, this compound is valuable in the development of pharmaceuticals and advanced materials due to its unique structural features and reactivity profile.
Formula:C10H14BClO2S
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