CAS 63555-59-9

1-Azetidineacetic acid, 3-[[(2Z)-(hydroxyimino)(4-hydroxyphenyl)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-, (αR,3S)-

Description:

1-Azetidineacetic acid, 3-[[(2Z)-(hydroxyimino)(4-hydroxyphenyl)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-, (αR,3S)- is a complex organic compound characterized by its azetidine ring structure, which contributes to its unique chemical properties. This compound features multiple functional groups, including an amino group, hydroxyl groups, and a ketone, which enhance its reactivity and potential biological activity. The presence of the hydroxyimino and phenylacetyl moieties suggests that it may exhibit significant interactions with biological targets, potentially influencing its pharmacological profile. The stereochemistry indicated by the (αR,3S) designation implies specific spatial arrangements of atoms, which can affect the compound's interactions and efficacy in biological systems. Additionally, the compound's solubility, stability, and reactivity can be influenced by its functional groups and overall molecular structure. Overall, this substance may have applications in medicinal chemistry, particularly in the development of therapeutic agents, although further studies would be necessary to fully elucidate its properties and potential uses.

Formula: C₁₉H₁₇N₃O₇

InChI: InChI=1S/C19H17N3O7/c23-12-5-1-10(2-6-12)15(21-29)17(25)20-14-9-22(18(14)26)16(19(27)28)11-3-7-13(24)8-4-11/h1-8,14,16,23-24,29H,9H2,(H,20,25)(H,27,28)/b21-15-/t14-,16+/m0/s1

InChI key: InChIKey=NMMOYDKOFASOBV-HKHZIIAMSA-N

SMILES: [C@@H](C(O)=O)(N1C(=O)[C@@H](NC(/C(=N\O)/C2=CC=C(O)C=C2)=O)C1)C3=CC=C(O)C=C3

Synonyms:

• (2R)-[(3S)-3-{[(2E)-2-(hydroxyimino)-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoazetidin-1-yl](4-hydroxyphenyl)ethanoic acid
• (2R)-[(3S)-3-{[(2Z)-2-(hydroxyimino)-2-(4-hydroxyphenyl)acetyl]amino}-2-oxoazetidin-1-yl](4-hydroxyphenyl)ethanoic acid
• 1-Azetidineacetic acid, 3-[[(2Z)-(hydroxyimino)(4-hydroxyphenyl)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-, (αR,3S)-
• 1-Azetidineacetic acid, 3-[[(hydroxyimino)(4-hydroxyphenyl)acetyl]amino]-α-(4-hydroxyphenyl)-2-oxo-, [3S-[1(S*),3R*(Z)]]-
• Nocardicin E

Nocardicin E

CAS: 63555-59-9

Formula: C₁₉H₁₇N₃O₇

Molecular weight: 399.3542

Ref: IN-DA003T9B

Nocardicin E

CAS: 63555-59-9

Nocardicin E is a β-lactam antibiotic, which is produced by the actinomycetes of the genus Nocardia. This antibiotic functions by inhibiting the biosynthesis of bacterial cell walls, specifically targeting the transpeptidation step in peptidoglycan synthesis, crucial for bacterial structural integrity. The compound acts as an irreversible inhibitor of the bacterial enzyme D-alanyl-D-alanine carboxypeptidase, contributing to its antibacterial efficacy, particularly against Gram-positive organisms. The mode of action interferes with the normal cross-linking of peptidoglycan layers, leading to cell lysis and death.

Formula: C₁₉H₁₇N₃O₇

Purity: Min. 95%

Molecular weight: 399.4 g/mol

Ref: 3D-NCA55559