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CAS 635681-64-0

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  • DNA ligase-IN-2
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    DNA ligase-IN-2

    CAS:
    <p>DNA ligase-IN-2 (compound 2) acts as a potent LigA inhibitor, effectively hindering the DNA-independent spontaneous adenylation activity of full-length LigA and the truncated enzyme LigA:AD with an IC50 of 29 nM. It also significantly suppresses the in vitro growth of Staphylococcus aureus, showing MIC values of 1 μg/mL for S. aureus ATCC 29213 and S. aureus ATCC 700699, while the MIC for Escherichia coli (E. coli) ATCC 25922 is &gt;64 μg/mL.</p>
    Formula:C13H8FN3O3
    Color and Shape:Solid
    Molecular weight:273.219

    Ref: TM-T204415