CAS 635702-64-6: Pazopanib hydrochloride

Description:Pazopanib hydrochloride is a small molecule tyrosine kinase inhibitor primarily used in the treatment of certain types of cancer, including renal cell carcinoma and soft tissue sarcoma. It functions by inhibiting multiple receptor tyrosine kinases, which are involved in tumor growth and angiogenesis. The substance is characterized by its molecular formula, which includes carbon, hydrogen, nitrogen, oxygen, and chlorine atoms, reflecting its complex structure. Pazopanib hydrochloride is typically administered orally and is known for its moderate to high solubility in various solvents, which facilitates its absorption in the gastrointestinal tract. The compound exhibits a relatively long half-life, allowing for once-daily dosing in clinical settings. Common side effects associated with its use may include hypertension, diarrhea, and fatigue, among others. As with many targeted therapies, monitoring for adverse effects and drug interactions is essential during treatment. Overall, pazopanib hydrochloride represents a significant advancement in targeted cancer therapy, providing a mechanism to inhibit tumor progression effectively.

Formula:C₂₁H₂₃N₇O₂S·ClH

InChI:InChI=1S/C21H23N7O2S.ClH/c1-13-5-6-15(11-19(13)31(22,29)30)24-21-23-10-9-20(25-21)27(3)16-7-8-17-14(2)28(4)26-18(17)12-16;/h5-12H,1-4H3,(H2,22,29,30)(H,23,24,25);1H

InChI key:InChIKey=MQHIQUBXFFAOMK-UHFFFAOYSA-N

SMILES:Cl.O=S(=O)(N)C1=CC(=CC=C1C)NC2=NC=CC(=N2)N(C=3C=CC=4C(=NN(C4C)C)C3)C

Synonyms:
5-((4-((2,3-Dimethyl-2H-indazol-6-yl)methylamino)pyrimidin-2-yl)amino)-2-methylbenzenesulfonamide monohydrochloride
5-(4-((2,3-dimethyl-2H-indazol-6-yl)(Methyl)amino)pyrimidin-2-ylamino)-2-Methylbenzenesulfonamide hydrochloride
5-[[4-[(2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino]pyrimidin-2-yl]amino]-2-methylbenzenesulfonamide hydrochloride
Benzenesulfonamide, 5-((4-((2,3-dimethyl-2H-indazol-6-yl)methylamino)-2-pyrimidinyl)amino)-2-methyl-,monohydrochloride
Benzenesulfonamide, 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-, hydrochloride (1:1)
Gw 786034B
Gw786034B
Pazopanib HCl
Unii-33Y9Anm545
Votrient
See more synonyms
Pazopanib hydrochloride

Found 13 products.

Product data	Purity	Price range	Estimated delivery
Pazopanib Hydrochloride REF: 54-OR1029257CAS: 635702-64-6	- - -	32.00 €~2,577.00 €	Mon 05 May 25
Pazopanib Hydrochloride REF: 54-BUP15707CAS: 635702-64-6	≥98%	158.00 €~536.00 €	Mon 05 May 25
Pazopanib Hydrochloride REF: 86-MM3391.00-0250CAS: 635702-64-6	- - -	1,487.00 €	Wed 07 May 25
Pazopanib Hydrochloride REF: 3B-P2243CAS: 635702-64-6	>95.0%(T)(HPLC)	50.00 €~151.00 €	Wed 07 May 25
Pazopanib hydrochloride REF: 7W-GX4287CAS: 635702-64-6	≥ 98.0% (dried basis)	74.00 €	Tue 13 May 25
Pazopanib HCl REF: 4Z-P-129035CAS: 635702-64-6	- - -	To inquire	Tue 13 May 25
GW786034B REF: TM-T6930CAS: 635702-64-6	99.87%	52.00 €~359.00 €	Tue 13 May 25
Pazopanib, Hydrochloride Salt REF: 10-F519777CAS: 635702-64-6	99.0%	To inquire	Wed 14 May 25
Pazopanib-d3 Hydrochloride REF: TR-P210927CAS: 635702-64-6	- - -	303.00 €~1,965.00 €	Wed 14 May 25
Pazopanib Hydrochloride REF: TR-P210926CAS: 635702-64-6	- - -	89.00 €~457.00 €	Wed 14 May 25
Pazopanib HCl REF: 3D-FD71644CAS: 635702-64-6	Min. 95%	143.00 €~1,003.00 €	Thu 15 May 25
Pazopanib HCl - Bio-X ™ REF: 3D-BP166746CAS: 635702-64-6	Min. 95%	147.00 €	Thu 15 May 25
Pazopanib Hydrochloride REF: 45-1500491CAS: 635702-64-6	- - -	- - -	Discontinued product