CAS 635705-72-5

(S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione

Description:

(S)-4-amino-2-(1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl)isoindoline-1,3-dione, with CAS number 635705-72-5, is a synthetic organic compound characterized by its complex molecular structure, which includes an isoindoline core. This compound features multiple functional groups, including an amino group, an ethoxy group, a methoxy group, and a methylsulfonyl moiety, contributing to its potential biological activity. The presence of stereocenters indicates that it exists in specific enantiomeric forms, with the (S) configuration being significant for its pharmacological properties. The compound's solubility, stability, and reactivity can vary based on the functional groups and their interactions. It may exhibit properties such as being a potential pharmaceutical agent, given its structural features that are often associated with bioactivity. Additionally, its synthesis and characterization would typically involve techniques such as NMR spectroscopy, mass spectrometry, and chromatography to confirm purity and structural integrity. Overall, this compound represents a class of molecules that may have applications in medicinal chemistry and drug development.

Desacetyl Apremilast ((S)-4-Amino-2-[1-(3-ethoxy-4-methoxyphenyl)-2-(methylsulfonyl)ethyl]isoindoline-1,3-dione)

CAS: 635705-72-5

Other aromatic organo-sulfur compounds (excluding pesticides)

Formula: C₂₀H₂₂N₂O₆S

Color and Shape: Yellow Powder

Molecular weight: 418.11986

Ref: 45-1A13780

Apremilast Impurity 11

CAS: 635705-72-5

Formula: C₂₀H₂₂N₂O₆S

Color and Shape: Yellow Solid

Molecular weight: 418.46

Ref: 4Z-A-182021

Desacetyl Apremilast

CAS: 635705-72-5

Formula: C₂₀H₂₂N₂O₆S

Molecular weight: 418.46

Ref: ST-EA-CP-A77011

Des-acetyl Apremilast

Controlled Product

CAS: 635705-72-5

Applications Des-acetyl Apremilast is the metabolite of Apremilast (A729700), which is an oral phosphodiesterase 4 inhibitor used in the treatment of psoriatic arthritis.
References Hoffmann, M., et al.: Xenobiotica, 41, 1063 (2011); Gan, E., et al.: BioDrugs, 27, 359 (2013); Pathan, E., et al.: Annal. Rheum. DIs., 72, 1475 (2013);

Formula: C₂₀H₂₂N₂O₆S

Color and Shape: Off-White To Yellow

Molecular weight: 418.46

Ref: TR-D289398

Des-acetyl apremilast

CAS: 635705-72-5

Apremilast is a drug product that belongs to the class of drugs called phosphodiesterase 4 inhibitors. It acts by inhibiting the enzyme phosphodiesterase 4 (PDE4) and therefore blocks the degradation of specific signaling molecules, such as cyclic adenosine monophosphate (cAMP). Apremilast has been shown to have anti-inflammatory properties in preclinical studies and is being developed for the treatment of inflammatory diseases, including rheumatoid arthritis. Apremilast is not active against gram-positive bacteria or some other types of bacteria. Apremilast has been shown to have a low potential for drug interactions with other drugs metabolized by cytochrome P450 enzymes.

Formula: C₂₀H₂₂N₂O₆S

Purity: Min. 95%

Molecular weight: 418.50 g/mol

Ref: 3D-KAB70572