CAS 635724-55-9

Esreboxetine succinate

Description:

Esreboxetine succinate is a pharmaceutical compound primarily recognized for its role as a selective norepinephrine reuptake inhibitor (NRI). It is utilized in the treatment of major depressive disorder and exhibits a mechanism of action that enhances norepinephrine levels in the synaptic cleft by inhibiting its reabsorption into presynaptic neurons. The substance is characterized by its chemical structure, which includes a succinate salt form that aids in its solubility and bioavailability. Esreboxetine has been studied for its efficacy and safety profile, showing potential benefits in alleviating depressive symptoms with a favorable side effect profile compared to traditional antidepressants. Its pharmacokinetics involve absorption, distribution, metabolism, and excretion processes that are crucial for determining dosing regimens. As with any medication, the therapeutic use of esreboxetine succinate should be guided by clinical evaluation and monitoring for adverse effects. Overall, it represents a significant advancement in the pharmacological management of depression, particularly for patients who may not respond adequately to other treatments.

Formula: C₂₃H₂₉NO₇

InChI: InChI=1/C19H23NO3.C4H6O4/c1-2-21-16-10-6-7-11-17(16)23-19(15-8-4-3-5-9-15)18-14-20-12-13-22-18;5-3(6)1-2-4(7)8/h3-11,18-20H,2,12-14H2,1H3;1-2H2,(H,5,6)(H,7,8)/t18-,19-;/m0./s1

SMILES: CCOc1ccccc1O[C@@H](c1ccccc1)[C@@H]1CNCCO1.C(CC(=O)O)C(=O)O

Synonyms:

• (2S)-2-[(S)-(2-Ethoxyphenoxy)phenylmethyl]morpholine succinate
• (2S)-2-[(S)-(2-ethoxyphenoxy)(phenyl)methyl]morpholine butanedioate (1:1)

(S,S)-Reboxetinesuccinate

Controlled Product

CAS: 635724-55-9

Applications SS,S)-reboxetinesuccinate (CAS# 635724-55-9) is a useful research chemical compound.

Formula: C₁₉H₂₃NO₃·C₄H₆O₄

Color and Shape: Neat

Molecular weight: 431.479

Ref: TR-S223865

Esreboxetine succinate

CAS: 635724-55-9

Ereboxetine succinate, a (+)-(S,S) reboxetine form, targets norepinephrine, for neuropathic pain and fibromyalgia.

Formula: C₂₃H₂₉NO₇

Color and Shape: Solid

Molecular weight: 431.485

Ref: TM-T31679L