CAS 635728-49-3
:Darunavir Ethanolate
Description:
Darunavir ethanolate is an antiretroviral medication primarily used in the treatment of HIV infection. It belongs to the class of protease inhibitors and is known for its ability to inhibit the HIV-1 protease enzyme, which is crucial for viral replication. The substance is characterized by its high potency against various strains of HIV, including those resistant to other antiretroviral agents. Darunavir ethanolate is typically administered in combination with other antiretroviral drugs to enhance its efficacy and reduce the risk of resistance development. The compound is a white to off-white crystalline powder, soluble in organic solvents, and has a relatively low solubility in water, which can affect its bioavailability. Its pharmacokinetic profile includes a long half-life, allowing for once-daily dosing in many treatment regimens. As with any medication, darunavir ethanolate may have side effects, including gastrointestinal disturbances and potential liver enzyme elevations, necessitating monitoring during treatment. Overall, it plays a significant role in modern HIV therapy, contributing to improved patient outcomes.
Formula:C27H37N3O7SC2H6O
Synonyms:- Prezista
- Unii-33O78Xf0Bw
- Carbamic acid, ((1S,2R)-3-(((4-aminophenyl)sulfonyl)(2-methylpropyl)amino)-2-hydroxy-1-(phenylmethyl)propyl)-, (3R,3aS,6aR)-hexahydrofuro(2,3-b)furan-3-yl ester, compd. with ethanol (1:1)
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Found 13 products.
Darunavir Ethanolate
CAS:Sulfonamides used as drugsFormula:C27H37N3O7S·C2H6OColor and Shape:White Beige PowderMolecular weight:593.27709(3R,3As,6Ar)-Hexahydrofuro[2,3-B]Furan-3-Yl ((2S,3R)-4-(4-Amino-N-Isobutylphenylsulfonamido)-3-Hydroxy-1-Phenylbutan-2-Yl)Carbamate Ethanolate
CAS:(3R,3As,6Ar)-Hexahydrofuro[2,3-B]Furan-3-Yl ((2S,3R)-4-(4-Amino-N-Isobutylphenylsulfonamido)-3-Hydroxy-1-Phenylbutan-2-Yl)Carbamate EthanolatePurity:98%Molecular weight:593.73g/molDarunavir Ethanolate
CAS:Formula:C27H37N3O7S·C2H6OColor and Shape:White To Off-White SolidMolecular weight:547.67 46.07Darunavir Ethanolate
CAS:<p>Darunavir Ethanolate (UIC 94017) is an HIV PROTEASE INHIBITOR that is used in the treatment of AIDS and HIV INFECTIONS.</p>Formula:C29H43N3O8SPurity:99.84% - 99.86%Color and Shape:SolidMolecular weight:593.74Darunavir Ethanolate
CAS:Controlled Product<p>Applications Darunavir Ethanolate (Prezista) is an HIV protease inhibitor. Derivative of Darunavir (D193500), a second generation HIV-1-protease inhibitor; structurally similar to amprenavir. Antiviral. It is a COVID19-related research product.<br>References Holmstock, N. et al.: Drug Metab. Disp., 40, 1473 (2012); Koh, Y., et al.: Antimicrob. Agents Chemother., 47, 3123 (2003), Arasteh, K., et al.: AIDS, 19, 943 (2005), Surleraux, D.L.N.G., et al.: J. Med. Chem., 48, 1813 (2005),<br></p>Formula:C27H37N3O7S·C2H6OColor and Shape:Off-WhiteMolecular weight:593.73Darunavir Ethanolate
CAS:<p>Darunavir is a HIV-1 protease inhibitor used orally in the treatment of patients with multi-drug resistant HIV-1 infection (Ghosh, 2007). It has also been shown to be effective against other infectious diseases such as hepatitis C virus and SARS coronavirus. Metabolized by cytochrome P450 3A (CYP3A) isoenzymes, darunavir is often administered together with ritonavir that prolongs its bioavaiability, giving a terminal elimination half-life (t1/2) of 15 hours (Back, 2008). The effect of darunavir on natural compounds such as matrix proteins and toll-like receptor activity has also been studied via high performance liquid chromatography (HPLC) experiments.</p>Formula:C27H37N3O7S·C2H6OPurity:Min. 95%Color and Shape:White PowderMolecular weight:593.73 g/molDarunavir ethanolate- Bio-X ™
CAS:<p>Darunavir is an HIV protease inhibitor that is used in the treatment of HIV-1 infection. This drug inhibits HIV-1 protease from binding and catalyzing by attaching to the enzyme and preventing HIV replication.</p>Formula:C27H37N3O7S·C2H6OPurity:Min. 99 Area-%Color and Shape:PowderMolecular weight:593.73 g/mol
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