CAS 636-54-4: Clopamide

Description: Clopamide is a sulfonamide diuretic medication primarily used to treat hypertension and edema associated with heart failure. It functions by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased urine output and decreased blood volume. Clopamide is characterized by its chemical formula, which includes a sulfonamide group, contributing to its pharmacological activity. The substance is typically administered orally and is known for its moderate potency compared to other diuretics. Clopamide has a relatively long half-life, allowing for once-daily dosing in many cases. Its side effects may include electrolyte imbalances, particularly hypokalemia, and potential allergic reactions due to its sulfonamide structure. As with any medication, it is essential to monitor patients for adverse effects and interactions with other drugs. Overall, Clopamide is an effective agent in managing fluid retention and hypertension, contributing to improved cardiovascular health when used appropriately.

Formula: C₁₄H₂₀ClN₃O₃S

InChI: InChI=1/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+

InChI key: InChIKey=LBXHRAWDUMTPSE-AOOOYVTPNA-N

SMILES: O=C(NN1C(C)CCCC1C)C2=CC=C(Cl)C(=C2)S(=O)(=O)N

Synonyms:

• 4-Chloro-N-(cis-2,6-dimethylpiperidino)-3-sulfamoylbenzamide
• 4-chloro-N-(2,6-dimethylpiperidin-1-yl)-3-sulfamoylbenzamide
• 4-chloro-N-(2,6-dimethylpiperidino)-3-sulphamoylbenzamide
• 4-chloro-N-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide
• Adurix
• Aquex
• Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,6-dimethyl-1-piperidinyl)-, cis-
• Benzamide, 3-(aminosulfonyl)-4-chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]-, rel-
• Benzamide, 4-chloro-N-(2,6-dimethylpiperidino)-3-sulfamoyl-, cis-
• Brinaldix
• Chlosudimeprimyl
• Clopamidum
• Dt 327
• N-(cis-2′,6′-Dimethyl-1′-piperidyl)-3-sulfamyl-4-chlorobenzamide
• rel-3-(Aminosulfonyl)-4-chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]benzamide

Clopamide for system suitability CRS

CAS: 636-54-4

• Formula: C₁₄H₂₀ClN₃O₃S
• Color and Shape: Crystalline Powder. White. Whitish. Powder., Crystalline Powder. White. Whitish. Powder.
• Molecular weight: 345.8449

Clopamide CRS

CAS: 636-54-4

• Formula: C₁₄H₂₀ClN₃O₃S
• Color and Shape: Crystalline Powder. White. Whitish. Powder., Crystalline Powder. White. Whitish. Powder.
• Molecular weight: 345.8449

Benzamide,3-(aminosulfonyl)-4-chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]-, rel-

CAS: 636-54-4

• Formula: C₁₄H₂₀ClN₃O₃S
• Purity: 98%
• Color and Shape: Solid
• Molecular weight: 345.8449

Clopamide

CAS: 636-54-4

• Formula: C₁₄H₂₀ClN₃O₃S
• Purity: ≥ 98.0%
• Color and Shape: White to off-white powder
• Molecular weight: 345.84

Clopamide

CAS: 636-54-4

• Formula: C₁₄H₂₀ClN₃O₃S
• Molecular weight: 345.85

Clopamide

CAS: 636-54-4

• Purity: ≥98%
• Molecular weight: 345.84g/mol

Clopamide

CAS: 636-54-4

Applications Antihypertensive; diuretic. References McNeil, J.J., et al.: Clin. Pharmacol. Ther., 42, 299 (1987), Crowder, …

• Formula: C₁₄H₂₀ClN₃O₃S
• Color and Shape: Light Yellow
• Molecular weight: 345.84

Clopamide

CAS: 636-54-4

Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.

• Formula: C₁₄H₂₀ClN₃O₃S
• Purity: 99.21%
• Color and Shape: White To Yellowish Crystalline Powder
• Molecular weight: 345.84

Clopamide

CAS: 636-54-4

Please enquire for more information about Clopamide including the price, delivery time and more detailed …

• Formula: C₁₄H₂₀ClN₃O₃S
• Purity: Min. 98 Area-%
• Color and Shape: White Powder
• Molecular weight: 345.85 g/mol