CAS 636-54-4

Clopamide

Description:

Clopamide is a sulfonamide diuretic medication primarily used to treat hypertension and edema associated with heart failure. It functions by inhibiting sodium reabsorption in the distal convoluted tubule of the nephron, leading to increased urine output and decreased blood volume. Clopamide is characterized by its chemical formula, which includes a sulfonamide group, contributing to its pharmacological activity. The substance is typically administered orally and is known for its moderate potency compared to other diuretics. Clopamide has a relatively long half-life, allowing for once-daily dosing in many cases. Its side effects may include electrolyte imbalances, particularly hypokalemia, and potential allergic reactions due to its sulfonamide structure. As with any medication, it is essential to monitor patients for adverse effects and interactions with other drugs. Overall, Clopamide is an effective agent in managing fluid retention and hypertension, contributing to improved cardiovascular health when used appropriately.

Formula: C₁₄H₂₀ClN₃O₃S

InChI: InChI=1/C14H20ClN3O3S/c1-9-4-3-5-10(2)18(9)17-14(19)11-6-7-12(15)13(8-11)22(16,20)21/h6-10H,3-5H2,1-2H3,(H,17,19)(H2,16,20,21)/t9-,10+

InChI key: InChIKey=LBXHRAWDUMTPSE-AOOOYVTPNA-N

SMILES: C(NN1[C@@H](C)CCC[C@H]1C)(=O)C2=CC(S(N)(=O)=O)=C(Cl)C=C2

Synonyms:

• 4-Chloro-N-(cis-2,6-dimethylpiperidino)-3-sulfamoylbenzamide
• 4-chloro-N-(2,6-dimethylpiperidin-1-yl)-3-sulfamoylbenzamide
• 4-chloro-N-(2,6-dimethylpiperidino)-3-sulphamoylbenzamide
• 4-chloro-N-[(2R,6S)-2,6-dimethylpiperidin-1-yl]-3-sulfamoylbenzamide
• Adurix
• Aquex
• Benzamide, 3-(aminosulfonyl)-4-chloro-N-(2,6-dimethyl-1-piperidinyl)-, cis-
• Benzamide, 3-(aminosulfonyl)-4-chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]-, rel-
• Benzamide, 4-chloro-N-(2,6-dimethylpiperidino)-3-sulfamoyl-, cis-
• Brinaldix
• Chlosudimeprimyl
• Clopamidum
• Dt 327
• N-(cis-2′,6′-Dimethyl-1′-piperidyl)-3-sulfamyl-4-chlorobenzamide

CLOPAMIDE FOR SYSTEM SUITABILITY CRS

CAS: 636-54-4

CLOPAMIDE FOR SYSTEM SUITABILITY CRS

Formula: C₁₄H₂₀ClN₃O₃S

Color and Shape: Crystalline Powder. White. Whitish. Powder., Crystalline Powder. White. Whitish. Powder.

Molecular weight: 345.8449

Ref: 41-Y0000848

CLOPAMIDE CRS

CAS: 636-54-4

CLOPAMIDE CRS

Formula: C₁₄H₂₀ClN₃O₃S

Color and Shape: Crystalline Powder. White. Whitish. Powder., Crystalline Powder. White. Whitish. Powder.

Molecular weight: 345.8449

Ref: 41-Y0000833

Benzamide,3-(aminosulfonyl)-4-chloro-N-[(2R,6S)-2,6-dimethyl-1-piperidinyl]-, rel-

CAS: 636-54-4

Formula: C₁₄H₂₀ClN₃O₃S

Purity: 98%

Color and Shape: Solid

Molecular weight: 345.8449

Ref: IN-DA01CB83

Clopamide

CAS: 636-54-4

Formula: C₁₄H₂₀ClN₃O₃S

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 345.84

Ref: 7W-GP4004

Clopamide

CAS: 636-54-4

Formula: C₁₄H₂₀ClN₃O₃S

Molecular weight: 345.85

Ref: 4Z-C-100001

Clopamide

CAS: 636-54-4

Clopamide

Purity: ≥98%

Molecular weight: 345.84g/mol

Ref: 54-BUP14719

Clopamide

Controlled Product

CAS: 636-54-4

Applications Antihypertensive; diuretic.
References McNeil, J.J., et al.: Clin. Pharmacol. Ther., 42, 299 (1987), Crowder, D., et al.: Curr. Med. Res. Opin., 6, 342 (1979),

Formula: C₁₄H₂₀ClN₃O₃S

Color and Shape: Light Yellow

Molecular weight: 345.84

Ref: TR-C587160

Clopamide

CAS: 636-54-4

Clopamide (Brinaldix) is a piperidine and sulfamoylbenzamide-based diuretic with thiazide-like diuretic activity.

Formula: C₁₄H₂₀ClN₃O₃S

Purity: 99.71%

Color and Shape: White To Yellowish Crystalline Powder

Molecular weight: 345.84

Ref: TM-T6086

Clopamide

CAS: 636-54-4

Clopamide is a diuretic drug that belongs to the group of protein genes. It is used in the treatment of chronic heart failure, low-density lipoprotein cholesterol and infectious diseases. Clopamide has been shown to increase the glomerular filtration rate by inhibiting the sodium citrate enzyme, which is involved in the formation of urine from blood plasma. This drug also reduces blood pressure by blocking angiotensin II receptors on vascular smooth muscle cells. Clopamide does not have any significant interactions with other drugs, although caution should be exercised when using it with cardiac drugs due to its effects on blood pressure.

Formula: C₁₄H₂₀ClN₃O₃S

Purity: Min. 98 Area-%

Color and Shape: White Powder

Molecular weight: 345.85 g/mol

Ref: 3D-FC20509