CAS 636-58-8

γ-L-Glutamyl-L-cysteine

Description:

γ-L-Glutamyl-L-cysteine, also known as gamma-glutamylcysteine, is a dipeptide composed of the amino acids glutamic acid and cysteine. It is characterized by the presence of a gamma linkage between the carboxyl group of glutamic acid and the amino group of cysteine, which distinguishes it from other peptide forms. This compound plays a crucial role in the biosynthesis of glutathione, a vital antioxidant in cells that helps protect against oxidative stress. γ-L-Glutamyl-L-cysteine is typically found in various biological systems and is involved in cellular processes such as detoxification and the regulation of cellular redox states. It is soluble in water and exhibits a relatively stable structure under physiological conditions. The compound is of interest in biochemical research and potential therapeutic applications, particularly in the context of oxidative stress-related diseases. Its CAS number, 636-58-8, is used for identification in chemical databases and regulatory contexts.

Formula: C₈H₁₄N₂O₅S

InChI: InChI=1S/C8H14N2O5S/c9-4(7(12)13)1-2-6(11)10-5(3-16)8(14)15/h4-5,16H,1-3,9H2,(H,10,11)(H,12,13)(H,14,15)/t4-,5-/m0/s1

InChI key: InChIKey=RITKHVBHSGLULN-WHFBIAKZSA-N

SMILES: [C@@H](NC(CC[C@@H](C(O)=O)N)=O)(C(O)=O)CS

Synonyms:

• <span class="text-smallcaps">L</smallcap>-Cysteine, <smallcap>L</span>-γ-glutamyl-
• <span class="text-smallcaps">L</smallcap>-Cysteine, N-<smallcap>L</span>-γ-glutamyl-
• <span class="text-smallcaps">L</smallcap>-γ-Glutamyl-<smallcap>L</span>-cysteine
• Cysteine, γ-glutamyl-
• Glutamine, N-(1-carboxy-2-mercaptoethyl)-
• Glutamine, N-(1-carboxy-2-mercaptoethyl)-, <span class="text-smallcaps">L</span>-
• L-Cysteine, N-L-gamma-glutamyl-
• L-gamma-glutamyl-L-cysteine
• gamma-Glu-cys
• gamma-Glutamylcysteine
• γ-<span class="text-smallcaps">L</smallcap>-Glutamyl-<smallcap>L</span>-cysteine
• γ-<span class="text-smallcaps">L</span>-Glutamyl-cysteine
• γ-Glu-Cys
• γ-Glutamylcysteine
• L-Cysteine, N-L-γ-glutamyl-
• Glutamine, N-(1-carboxy-2-mercaptoethyl)-, L-

(Des-Gly)-Glutathione (reduced)

CAS: 636-58-8

Bachem ID: 4025354.

Formula: C₈H₁₄N₂O₅S

Purity: 98.0%

Color and Shape: White Lyophilisate

Molecular weight: 250.28

Ref: 01-4025354

γ-GLU-CYS TRIFLUOROACETATE SALT

CAS: 636-58-8

Formula: C₈H₁₄N₂O₅S

Purity: 80%

Color and Shape: Solid

Molecular weight: 250.2722

Ref: IN-DA00EC5W

Glutathione EP Impurity D

CAS: 636-58-8

Formula: C₈H₁₄N₂O₅S

Color and Shape: White To Off-White Solid

Molecular weight: 250.27

Ref: 4Z-PG-253

γ-glutamylcysteine

CAS: 636-58-8

γ-glutamylcysteine

Purity: ≥95%

Molecular weight: 250.27g/mol

Ref: 54-OR1006523

γ-Glutamylcysteine

CAS: 636-58-8

Gamma-Glutamylcysteine is a natural dipeptide, a precursor to glutathione (GSH) and a cofactor for GPx. anti-inflammatory effects by upregulating IL-10.

Formula: C₈H₁₄N₂O₅S

Color and Shape: Solid

Molecular weight: 250.27

Ref: TM-T38024

Glutathione EP Impurity D-15N-d3

CAS: 636-58-8

Formula: C₈H₁₁D₃N₁₅NO₅S

Molecular weight: 254.28

Ref: 4Z-PG-2531

γ-L-glutamyl-L-cysteine

CAS: 636-58-8

Gamma-L-glutamyl-L-cysteine (γGluCys) is a glutathione precursor that can be used in the treatment of oxidative injury. It is synthesized from glutamate and cysteine by the enzyme γ-glutamylcysteine synthetase. γGluCys has been shown to have antioxidant properties and to protect cells against oxidative injury. It also has inhibitory properties on inflammatory enzymes such as cyclooxygenase, lipoxygenase, and nitric oxide synthase. Gamma-L-glutamyl-L-cysteine has been shown to be an effective inhibitor of various pharmacological agents, including acetaminophen and morphine.

Formula: C₈H₁₄N₂O₅S

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 250.27 g/mol

Ref: 3D-FG29587

γ-glutamylcysteine

CAS: 636-58-8

Purity: 95%

Molecular weight: 250.2700043

Ref: 10-F614437

L-​γ-​Glutamyl-L-​cysteine

Controlled Product

CAS: 636-58-8

Formula: C₈H₁₄N₂O₅S

Color and Shape: Neat

Molecular weight: 250.27

Ref: TR-G384065

Glutathione EP Impurity D

CAS: 636-58-8

Formula: C₈H₁₄N₂O₅S

Molecular weight: 250.3

Ref: ST-EA-CP-G55004