CAS 636-93-1

5-Nitroguaiacol

Description:

5-Nitroguaiacol is an organic compound characterized by its nitro and guaiacol functional groups. It is a pale yellow to brown solid at room temperature and is soluble in organic solvents such as ethanol and acetone, but has limited solubility in water. The compound features a methoxy group (-OCH3) and a hydroxyl group (-OH) attached to a benzene ring, which contributes to its aromatic properties. 5-Nitroguaiacol is primarily used in the synthesis of various pharmaceuticals and agrochemicals, as well as in research applications due to its potential as an intermediate in organic synthesis. It exhibits antioxidant properties and has been studied for its biological activities, including antimicrobial effects. However, like many nitro compounds, it may pose environmental and health risks, necessitating careful handling and disposal. Its chemical structure allows for various reactions, making it a versatile compound in synthetic organic chemistry.

Formula: C₇H₇NO₄

InChI: InChI=1S/C7H7NO4/c1-12-7-3-2-5(8(10)11)4-6(7)9/h2-4,9H,1H3

InChI key: InChIKey=KXKCTSZYNCDFFG-UHFFFAOYSA-N

SMILES: N(=O)(=O)C1=CC(O)=C(OC)C=C1

Synonyms:

• 2-Hydroxy-4-nitroanisole
• 3-Hydroxy-4-methoxynitrobenzene
• 3-Hydroxy-4-methoxynitrobenzene~5-Nitroguaiacol
• 3-Nitro-6-methoxyphenol
• 4-Nitro-2-hydroxyanisole
• 5-Nitroguaiacol
• 5-Nitroguaiacol (3-Hydroxy-4-methoxynitrobenzene)
• Guaiacol, 5-nitro-
• Phenol, 2-methoxy-5-nitro-
• 2-Methoxy-5-nitrophenol

5-Nitroguaiacol

CAS: 636-93-1

Formula: C₇H₇NO₄

Purity: >98.0%(T)

Color and Shape: Light yellow to Amber to Dark green powder to crystal

Molecular weight: 169.14

Ref: 3B-N0498

Phenol, 2-​methoxy-​5-​nitro-

CAS: 636-93-1

Formula: C₇H₇NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 169.1348

Ref: IN-DA003HJD

2-Methoxy-5-nitrophenol

CAS: 636-93-1

Formula: F·W

Molecular weight: 169.14

Ref: 7W-GK9790

2-Methoxy-5-nitrophenol

CAS: 636-93-1

2-Methoxy-5-nitrophenol

Formula: C₇H₇NO₄

Purity: 98%

Color and Shape: light brown to brown solid

Molecular weight: 169.13g/mol

Ref: 54-OR1904

2-Methoxy-5-nitrophenol

CAS: 636-93-1

2-Methoxy-5-nitrophenol (2MNOP) is a compound that has been shown to inhibit the growth of bacteria in nutrient solutions by reducing the activity of glutamate pyruvate transaminase and pyridoxine hydrochloride. 2MNOP is a potent inhibitor of bacterial enzyme activities, such as neutral ph, hydrochloric acid, nitro, and toxicity studies. It is not active against eukaryotic cells or plants. The uptake of 2MNOP is enhanced by the presence of diamine tetraacetic acid and ethylene diamine. 2MNOP has also been shown to be effective against multi-walled carbon nanotubes.

Formula: C₇H₇NO₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 169.13 g/mol

Ref: 3D-FM39650

2-Methoxy-5-nitrophenol

CAS: 636-93-1

Formula: C₇H₇NO₄

Purity: 97%

Color and Shape: Crystalline

Molecular weight: 169.136

Ref: 10-F079661

2-Methoxy-5-nitrophenol

CAS: 636-93-1

Applications 2-Methoxy-5-nitrophenol is used in the synthesis of potent VEGF and tyrosine kinase inhibitors. Also used in the synthesis of GABA analogues and phosphodiesterase inhibitors such as rolipram.
References Hennequin, L. et al.: J. Med. Chem., 42 , 5369 (1999); Garcia, A. et al.: J. Org. Chem., 70, 1050 (2005);

Formula: C₇H₇NO₄

Color and Shape: Light Yellow

Molecular weight: 169.13

Ref: TR-M266285

2-Methoxy-5-Nitrophenol

CAS: 636-93-1

Formula: C₇H₇NO₄

Molecular weight: 169.14

Ref: ST-EA-CP-B80006