CAS 636-97-5

4-Nitrobenzoic acid hydrazide

Description:

4-Nitrobenzoic acid hydrazide is an organic compound characterized by its hydrazide functional group attached to a nitro-substituted benzoic acid. It typically appears as a crystalline solid and is known for its potential applications in pharmaceuticals and organic synthesis. The presence of the nitro group contributes to its reactivity, making it useful in various chemical reactions, including coupling reactions and as a precursor for more complex molecules. The compound is generally soluble in polar solvents, such as water and alcohols, but may have limited solubility in non-polar solvents. Its molecular structure includes a hydrazine moiety, which can participate in further chemical transformations, enhancing its utility in synthetic chemistry. Additionally, 4-Nitrobenzoic acid hydrazide may exhibit biological activity, which has been explored in various studies, indicating its potential as a lead compound in drug development. Safety precautions should be observed when handling this compound, as it may pose health risks if ingested or inhaled.

Formula: C₇H₇N₃O₃

InChI: InChI=1S/C7H7N3O3/c8-9-7(11)5-1-3-6(4-2-5)10(12)13/h1-4H,8H2,(H,9,11)

InChI key: InChIKey=FKZXYJYTUSGIQE-UHFFFAOYSA-N

SMILES: C(NN)(=O)C1=CC=C(N(=O)=O)C=C1

Synonyms:

• (p-Nitrobenzoyl)hydrazine
• 2,5-dihydro-3H-imidazo[1,2-b]pyrazole
• 4-Nireobenzoylhydrazine
• 4-Nitrobenzenecarboxylic acid hydrazide
• 4-Nitrobenzocarboxyhydrazide
• 4-Nitrobenzohydrazide
• 4-Nitrobenzoic acid hydrazide
• 4-Nitrobenzoic hydrazide
• 4-Nitrobenzoyl hydrazide
• 4-Nitrobenzoylhydrazine
• Benzoic acid, 4-nitro-, hydrazide
• Benzoic acid, p-nitro-, hydrazide
• INHd 18
• NSC 9804
• p-Nitrobenzhydrazide
• p-Nitrobenzohydrazide
• p-Nitrobenzoic acid hydrazide
• p-Nitrobenzoic hydrazide

4-Nitrobenzhydrazide

CAS: 636-97-5

Formula: C₇H₇N₃O₃

Purity: >98.0%(T)(HPLC)

Color and Shape: Light orange to Yellow to Green powder to crystaline

Molecular weight: 181.15

Ref: 3B-N0149

4-Nitrobenzhydrazide, 98+%

CAS: 636-97-5

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₇H₇N₃O₃

Purity: 98+%

Color and Shape: Yellow, Powder

Molecular weight: 181.15

Ref: 02-A18016

4-Nitrobenzhydrazide

CAS: 636-97-5

4-Nitrobenzhydrazide

Purity: ≥95%

Color and Shape: Solid

Molecular weight: 181.15g/mol

Ref: 54-OR110966

4-Nitrobenzoic hydrazide

CAS: 636-97-5

Formula: C₇H₇N₃O₃

Purity: 95.0%

Color and Shape: Solid

Molecular weight: 181.151

Ref: 10-F018901

4-Nitrobenzhydrazide

CAS: 636-97-5

4-Nitrobenzhydrazide is a diazonium salt that binds to DNA. 4-Nitrobenzhydrazide has been shown to have tuberculostatic activity against Mycobacterium tuberculosis and Mycobacterium bovis, with an IC50 of 0.5 mM. 4-Nitrobenzhydrazide binds to the DNA by intramolecular hydrogen bonding and intermolecular hydrogen bonding. It is chemically stable in methanol solvent, but unstable in water and organic solvents. The binding affinity of 4-nitrobenzhydrazide for DNA is very high, with a Kd value of 0.1 μM. Nitrogen atoms are present at each site where the diazonium salt interacts with the DNA backbone, while the molecule contains two dihedral angles and two molecules that are connected through hydrogen bonds.

Formula: C₇H₇N₃O₃

Purity: Min. 98 Area-%

Color and Shape: Yellow Powder

Molecular weight: 181.15 g/mol

Ref: 3D-FN07838