CAS 63612-50-0: Nilutamide
Description:Nilutamide is a non-steroidal antiandrogen medication primarily used in the treatment of prostate cancer. It functions by inhibiting the action of androgens, such as testosterone, at the cellular level, thereby slowing the growth of hormone-sensitive tumors. The chemical formula of nilutamide is C12H10F2N2O2, and it features a distinctive structure that includes a 4-nitroaniline moiety. Nilutamide is typically administered orally and is known for its relatively long half-life, allowing for once-daily dosing. Common side effects may include hot flashes, gastrointestinal disturbances, and liver function abnormalities. It is important to monitor liver enzymes during treatment due to the potential for hepatotoxicity. Additionally, nilutamide has been associated with visual disturbances, particularly in the early stages of therapy. As with any medication, the benefits must be weighed against the risks, and it should be prescribed and monitored by a healthcare professional.
Formula:C12H10F3N3O4
InChI:InChI=1S/C12H10F3N3O4/c1-11(2)9(19)17(10(20)16-11)6-3-4-8(18(21)22)7(5-6)12(13,14)15/h3-5H,1-2H3,(H,16,20)
InChI key:InChIKey=XWXYUMMDTVBTOU-UHFFFAOYSA-N
SMILES:O=C1NC(C(=O)N1C2=CC=C(C(=C2)C(F)(F)F)N(=O)=O)(C)C
- Synonyms:
- 1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazolidine-2,5-dione
- 1-(3-Trifluoromethyl-4-nitrophenyl)-4,4-dimethylimidazoline-2,5-dione
- 2,4-Imidazolidinedione, 5,5-dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-
- 5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]-2,4-imidazolidinedione
- 5,5-Dimethyl-3-[4-nitro-3-(trifluoromethyl)phenyl]imidazolidine-2,4-dione
- Anandron
- Nilandron
- Nilandrone
- Nilumide
- Ru 23908
- See more synonyms
- Ru 23908-10
- Nilutamide
