CAS 63619-84-1

Trioxifene

Description:

Trioxifene, with the CAS number 63619-84-1, is a synthetic compound that belongs to the class of selective estrogen receptor modulators (SERMs). It is primarily characterized by its ability to bind to estrogen receptors, exhibiting both estrogenic and anti-estrogenic properties depending on the target tissue. This dual action makes Trioxifene of interest in the context of hormone-related conditions, particularly in breast cancer treatment, where it may help inhibit tumor growth in estrogen-dependent cancers. The compound is typically studied for its pharmacological effects, including its potential to modulate bone density and lipid profiles, making it a candidate for osteoporosis treatment as well. Trioxifene's chemical structure includes multiple functional groups that contribute to its biological activity, and it is often evaluated in preclinical and clinical studies to assess its efficacy and safety profile. As with many SERMs, the therapeutic applications of Trioxifene are accompanied by a need for careful consideration of side effects and interactions with other medications.

Formula: C₃₀H₃₁NO₃

InChI: InChI=1S/C30H31NO3/c1-33-25-13-8-23(9-14-25)28-17-12-22-6-2-3-7-27(22)29(28)30(32)24-10-15-26(16-11-24)34-21-20-31-18-4-5-19-31/h2-3,6-11,13-16H,4-5,12,17-21H2,1H3

InChI key: InChIKey=IHGLINDYFMDHJG-UHFFFAOYSA-N

SMILES: C(=O)(C1=C(CCC=2C1=CC=CC2)C3=CC=C(OC)C=C3)C4=CC=C(OCCN5CCCC5)C=C4

Synonyms:

• (3,4-Dihydro-2-(4-methoxyphenyl)-1-naphthyl)(4-(2-(1-pyrrolidinyl)ethyl)phenyl)keton
• 3,4-Dihydro-2-(P-Methoxyphenyl)-1-Naphthyl P-(2-(1-Pyrrolidinyl)Ethoxy)Phenyl)Ketone
• Lilly 88571
• Methanone, (3,4-dihydro-2-(4-methoxyphenyl)-1-naphthalenyl)(4-(2-(1-pyrrolidinyl)ethoxy)phenyl)-
• Trioxifene [INN]
• Trioxifeno
• Trioxifeno [INN-Spanish]
• Trioxifenum
• Trioxifenum [INN-Latin]
• [2-(4-Methoxyphenyl)-3,4-Dihydronaphthalen-1-Yl]{4-[2-(Pyrrolidin-1-Yl)Ethoxy]Phenyl}Methanone
• [2-(4-Methoxyphenyl)-3,4-Dihydronaphthalen-1-Yl]{4-[2-(Pyrrolidin-1-Yl)Ethoxy]Phenyl}Methanone Methanesulfonate (1:1)
• [3,4-Dihydro-2-(4-methoxyphenyl)-1-naphthalenyl][4-[2-(1-pyrrolidinyl)ethoxy]phenyl]methanone

Trioxifene

Controlled Product

CAS: 63619-84-1

Formula: C₃₀H₃₁NO₃

Color and Shape: Neat

Molecular weight: 453.572

Ref: TR-T806540

Trioxifene

CAS: 63619-84-1

Trioxifene is an analog of tamoxifen, a selective estrogen receptor modulator (SERM) that has been used in breast cancer treatment. Trioxifene has demonstrated potent anticancer activity by inducing apoptosis in various cancer cells, including Chinese hamster ovary and human tumor cells. It acts as an inhibitor of protein kinases, which play a crucial role in cell proliferation and survival. Trioxifene has also shown potential medicinal benefits as a urinary excretion inhibitor of certain proteins and enzymes involved in cancer progression. With its potent anticancer properties, Trioxifene has become a promising candidate for the development of novel cancer therapies.

Formula: C₃₀H₃₁NO₃

Purity: Min. 95%

Molecular weight: 453.6 g/mol

Ref: 3D-NCA61984