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CAS 63638-91-5

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Brofaromine

Description:
Brofaromine is a chemical compound classified as a selective monoamine oxidase inhibitor (MAOI), primarily used in the treatment of depression. Its chemical structure features a phenyl ring and a piperidine moiety, which contribute to its pharmacological activity. Brofaromine works by inhibiting the enzyme monoamine oxidase, leading to increased levels of neurotransmitters such as serotonin, norepinephrine, and dopamine in the brain, which can enhance mood and alleviate depressive symptoms. The compound is known for its relatively favorable side effect profile compared to other MAOIs, as it is less likely to cause dietary restrictions associated with tyramine. Brofaromine has been studied for its potential neuroprotective effects and may also have applications in treating anxiety disorders. However, like all MAOIs, it requires careful monitoring for interactions with certain foods and medications. Overall, Brofaromine represents a significant option in the pharmacotherapy of mood disorders, although its use may be limited by the availability of newer antidepressants.
Formula:C14H16BrNO2
InChI:InChI=1S/C14H16BrNO2/c1-17-11-6-10-7-13(9-2-4-16-5-3-9)18-14(10)12(15)8-11/h6-9,16H,2-5H2,1H3
InChI key:InChIKey=WZXHSWVDAYOFPE-UHFFFAOYSA-N
SMILES:BrC1=C2C(C=C(O2)C3CCNCC3)=CC(OC)=C1
Synonyms:
  • 4-(7-Bromo-5-Methoxy-1-Benzofuran-2-Yl)Piperidine
  • 4-(7-Bromo-5-methoxy-2-benzofuranyl)piperidine
  • Brofaremine
  • Brofaromina
  • Brofaromina [Spanish]
  • Brofaromine [INN]
  • Brofarominum
  • Brofarominum [Latin]
  • Cgp 11305
  • Piperidine, 4-(7-bromo-5-methoxy-2-benzofuranyl)-
  • See more synonyms
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