CAS 636582-62-2

Mosapride citrate dihydrate

Description:

Mosapride citrate dihydrate is a pharmaceutical compound primarily used as a gastroprokinetic agent, which enhances gastrointestinal motility. It is a derivative of mosapride, a selective serotonin 5-HT4 receptor agonist, and is often utilized in the treatment of functional gastrointestinal disorders, such as dyspepsia and gastroesophageal reflux disease (GERD). The dihydrate form indicates that the compound contains two molecules of water, which can influence its solubility and stability. Mosapride citrate dihydrate is characterized by its ability to stimulate peristalsis in the gastrointestinal tract, thereby improving the movement of food through the digestive system. It is generally well-tolerated, with a side effect profile that may include mild gastrointestinal disturbances. The compound's pharmacokinetics involve absorption in the gastrointestinal tract, with metabolism primarily occurring in the liver. As with any medication, it is essential to consider contraindications and potential interactions with other drugs. Overall, mosapride citrate dihydrate plays a significant role in managing certain gastrointestinal conditions, contributing to improved patient outcomes.

Formula: C₂₇H₃₃ClFN₃O₁₀

InChI: InChI=1/C21H25ClFN3O3.C6H8O7.2H2O/c1-2-28-20-10-19(24)18(22)9-17(20)21(27)25-11-16-13-26(7-8-29-16)12-14-3-5-15(23)6-4-14;7-3(8)1-6(13,5(11)12)2-4(9)10;;/h3-6,9-10,16H,2,7-8,11-13,24H2,1H3,(H,25,27);13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);2*1H2

InChI key: InChIKey=SLDCUFRDADJSBX-UHFFFAOYSA-N

SMILES: C(NCC1CN(CC2=CC=C(F)C=C2)CCO1)(=O)C3=C(OCC)C=C(N)C(Cl)=C3.C(CC(O)=O)(CC(O)=O)(C(O)=O)O.O

Synonyms:

• (+-)-4-Amino-5-Chloro-2-Ethoxy-N-((4-(4-Fluorobenzyl)-2-Morpholinyl)Methyl)B
• 4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluorobenzyl)morpholin-2-yl]methyl}benzamide 2-hydroxypropane-1,2,3-tricarboxylate (1:1)
• 4-amino-5-chloro-2-ethoxy-N-{[4-(4-fluorobenzyl)morpholin-2-yl]methyl}benzamide 2-hydroxypropane-1,2,3-tricarboxylate dihydrate (salt)
• As4370
• Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, 2-hydroxy-1,2,3-propanetricarboxylate (1:1), dihydrate
• Benzamide, 4-amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]-2-morpholinyl]methyl]-, 2-hydroxy-1,2,3-propanetricarboxylate, hydrate (1:1:2)
• Benzamide,4-Amino-5-Chloro-2-Ethoxy-N-((4-((4-Fluorophenyl)Methyl)-2-Morpholin
• Enzamidecitrate
• Mosapride citrate dihydrate
• Yl)Methyl)-,2-Hydroxy-1,2,3-Propanetricarboxylate(1:1)
• 4-Amino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)methyl]morpholin-2-yl]methyl]benzamide citrate dihydrate
• MOSAPRIDE CITRATE DIHYDRATE USP/EP/BP
• Mosapride citrate salt dihydrate
• Mosapride dihydrate citrate
• 4-AMino-5-chloro-2-ethoxy-N-[[4-[(4-fluorophenyl)Methyl]-2-Morpholinyl]Methyl]benzaMide 2-Hydroxy-1,2,3-propanetricarboxylate Hydrate

Mosapride citrate dihydrate

CAS: 636582-62-2

Mosapride Citrate, a 5-HT4 agonist, boosts gut movement by enhancing acetylcholine release.

Formula: C₂₇H₃₅ClFN₃O₁₁

Purity: 98%

Color and Shape: Solid

Molecular weight: 632.04

Ref: TM-T6597L

Mosapride citrate salt dihydrate

CAS: 636582-62-2

Purity: ≥ 98.0%

Color and Shape: White to beige powder or crystalline powder

Molecular weight: 650.05

Ref: 7W-GP7199

Mosapride Citrate Dihydrate

Controlled Product

CAS: 636582-62-2

Applications A selective 5-HT4 receptor agonist. Gastroprokinetic.
References Yoshida, N., et al.: Arch. Int. Pharmacodyn. Ther., 300, 51 (1989), Yatera, S., et al.: Japan. Pharmacol. Ther., 21, 21 (1993), Ruth, M., et al.: Aliment Pharmacol. Ther., 12, 35 (1998),

Formula: C₂₁H₂₅ClFN₃O₃·C₆H₈O₇·2H₂O

Color and Shape: White To Off-White

Molecular weight: 650.05

Ref: TR-M730995

Mosapride citrate dihydrate

CAS: 636582-62-2

Mosapride is an oral drug for the treatment of hyperproliferative diseases, such as a cavity. It is used to stimulate insulin sensitivity and to reduce insulin resistance. Mosapride has been shown to inhibit oxidative phosphorylation in vitro. Mosapride also acts on 5-HT4 receptors and has been shown to be a potent 5-HT4 receptor agonist. This drug contains crystalline cellulose, which is a filler that can cause allergic reactions. Other ingredients are proton and particle, which are excipients that may cause allergic reactions or other side effects, including dizziness and headache.

Formula: C₂₁H₂₅ClFN₃O₃C₆H₈O₇(H₂O)₂

Purity: Min. 95%

Molecular weight: 650.05 g/mol

Ref: 3D-LAB58262